A general procedure for conversion of S-glycosyl isothiourea derivatives into thioglycosides, thiooligosaccharides and glycosyl thioesters

被引：0

作者：

Ibatullin, FM ^{[1
]}

Selivanov, SI

Shavva, AG

机构：

[1] Petersburg Nucl Phys Inst, Mol & Radiat Biophys Div, Gatchina 188300, Russia

[2] St Petersburg State Univ, Dept Chem, St Petersburg 198904, Russia

来源：

SYNTHESIS-STUTTGART | 2001年 / 03期

关键词：

alkyl halides; carbohydrates; thioglycosides; thiooligosaccharides; thioesters;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple procedure for conversion of S-glycosyl isothiourea derivatives into thioglycosides by promotion with triethylamine is described. The reaction conditions allow the synthesis of glycosyl thioesters and some thioglycosides, which cannot be prepared using the traditional approach. The procedure has been successfully applied for preparation of thiooligosaccharides, shown by syntheses of methyl 4-thio-alpha -cellobioside and methyl 4-thio-alpha -lactoside derivatives.

引用

页码：419 / 422

页数：4

共 71 条

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