Development and Validation of GC-MS Method for Determination of Metoprolol in Human Urine

被引：8

作者：

Yilmaz, Bilal ^{[1
]}

Arslan, Sakir ^{[2
]}

机构：

[1] Ataturk Univ, Fac Pharm, Dept Analyt Chem, TR-25240 Erzurum, Turkey

[2] Ataturk Univ, Fac Med, Dept Cardiol, TR-25240 Erzurum, Turkey

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 2010年 / 48卷 / 08期

关键词：

LIQUID-CHROMATOGRAPHIC ASSAY; SOLID-PHASE EXTRACTION; MASS-SPECTROMETRY; HUMAN PLASMA; BETA-BLOCKERS; METABOLITES; QUANTIFICATION; PROPRANOLOL; ENANTIOMERS; ATENOLOL;

D O I：

10.1093/chromsci/48.8.613

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：613 / 617

页数：5

共 19 条

[11] Determination of metoprolol, and its four metabolites in dog plasma [J].

Fang, J ;

Semple, HA ;

Song, JX .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2004, 809 (01) :9-14

[12] Liquid chromatography tandem mass spectrometry method for simultaneous determination of metoprolol tartrate and ramipril in human plasma [J].

Gowda, K. Veeran ;

Mandal, Uttam ;

Selvan, P. Senthamil ;

Solomon, W. D. Sam ;

Ghosh, Animesh ;

Sarkar, Amlan Kanti ;

Agarwal, Angita ;

Rao, T. Nageswar ;

Pal, Tapan Kumar .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 858 (1-2) :13-21

[13] Development and validation of a stereoselective liquid chromatography-tandem mass spectrometry assay for quantification of S- and R-metoprolol in human plasma [J].

Jensen, Berit P. ;

Sharp, Caroline F. ;

Gardiner, Sharon J. ;

Begg, Evan J. .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2008, 865 (1-2) :48-54

[14] Quantitation of atenolol, metoprolol, and propranolol in postmortem human fluid and tissue specimens via LC/APCI-MS [J].

Johnson, RD ;

Lewis, RJ .

FORENSIC SCIENCE INTERNATIONAL, 2006, 156 (2-3) :106-117

[15] Determination of metoprolol enantiomers in human urine by GC-MS using (-)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride as a chiral derivatizing agent [J].

Kim, KH ;

Lee, JH ;

Ko, MY ;

Shin, KS ;

Kang, JS ;

Mar, WC ;

Youm, JR .

CHROMATOGRAPHIA, 2002, 55 (1-2) :81-85

[16] Simultaneous screening analysis of multiple β-blockers in urine by gas chromatography-mass spectrometry in selected ion monitoring mode [J].

Paik, Man-Jeong ;

Lee, Jinwoo ;

Kim, Kyoung-Rae .

ANALYTICA CHIMICA ACTA, 2007, 601 (02) :230-233

[17] REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY TO QUANTITATE DIASTEREOMERIC DERIVATIVES OF METOPROLOL ENANTIOMERS IN PLASMA [J].

SCHUSTER, D ;

MODI, MW ;

LALKA, D ;

GENGO, FM .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 433 :318-325

[18]

*US DEP HHS, 2001, GUID IND BIOAN

[19]

*USP, USP28NF23, P1281

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