Development and Validation of GC-MS Method for Determination of Metoprolol in Human Urine

被引:8
作者
Yilmaz, Bilal [1 ]
Arslan, Sakir [2 ]
机构
[1] Ataturk Univ, Fac Pharm, Dept Analyt Chem, TR-25240 Erzurum, Turkey
[2] Ataturk Univ, Fac Med, Dept Cardiol, TR-25240 Erzurum, Turkey
关键词
LIQUID-CHROMATOGRAPHIC ASSAY; SOLID-PHASE EXTRACTION; MASS-SPECTROMETRY; HUMAN PLASMA; BETA-BLOCKERS; METABOLITES; QUANTIFICATION; PROPRANOLOL; ENANTIOMERS; ATENOLOL;
D O I
10.1093/chromsci/48.8.613
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:613 / 617
页数:5
相关论文
共 19 条
[1]   HPLC quantification of metoprolol with solid-phase extraction for the drug monitoring of pediatric patients [J].
Albers, S ;
Elshoff, JP ;
Völker, C ;
Richter, A ;
Läer, S .
BIOMEDICAL CHROMATOGRAPHY, 2005, 19 (03) :202-207
[2]   Gas chromatographic-mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol [J].
Angier, MK ;
Lewis, RJ ;
Chaturvedi, AK ;
Canfield, DV .
JOURNAL OF ANALYTICAL TOXICOLOGY, 2005, 29 (06) :517-521
[3]  
[Anonymous], 1996, P INT C HARM ICH COM
[4]   Stereoselective analysis of metoprolol and its metabolites in rat plasma with application to oxidative metabolism [J].
Boralli, VB ;
Coelho, EB ;
Cerqueira, PM ;
Lanchote, VL .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2005, 823 (02) :195-202
[5]   Development, validation and analytical error function of two chromatographic methods with fluorimetric detection for the determination of bisoprolol and metoprolol in human plasma [J].
Braza, AJ ;
Modamio, P ;
Lastra, CF ;
Mariño, EL .
BIOMEDICAL CHROMATOGRAPHY, 2002, 16 (08) :517-522
[6]  
*BRIT PHARM COMM, 2005, BRIT PHARM
[7]   Efficient high-performance liquid chromatographic assay for the simultaneous determination of metoprolol and two main metabolites in human urine by solid-phase extraction and fluorescence detection [J].
Chiu, FCK ;
Damani, LA ;
Li, RC ;
Tomlinson, B .
JOURNAL OF CHROMATOGRAPHY B, 1997, 696 (01) :69-74
[8]   N-METHYL-N-TRIMETHYLSILYL-TRIFLUOROACETAMIDE A NEW SILYLATING AGENT FROM SERIES OF SILYLATED AMIDES [J].
DONIKE, M .
JOURNAL OF CHROMATOGRAPHY, 1969, 42 (01) :103-&
[9]   Determination of three β-blockers in biofluids and solid tissues by liquid chromatography-electrospray-mass spectrometry [J].
Dupuis, C ;
Gaulier, JM ;
Pélissier-Alicot, AL ;
Marquet, P ;
Lachâtre, U .
JOURNAL OF ANALYTICAL TOXICOLOGY, 2004, 28 (08) :674-679
[10]   SELECTED ION MONITORING OF METOPROLOL AND 2 METABOLITES IN PLASMA AND URINE USING DEUTERATED INTERNAL STANDARDS [J].
ERVIK, M ;
HOFFMANN, KJ ;
KYLBERGHANSSEN, K .
BIOMEDICAL MASS SPECTROMETRY, 1981, 8 (07) :322-326