Anaplastic large cell lymphoma: A unique presentation with urinary bladder involvement - A case report

被引：11
作者：
Murphy, AJ
O'Neill, P
O'Brien, F
Enright, H
Jeffers, M
Thornhill, JA
Loftus, BM
机构：
[1] Adelaide & Meath Hosp, Dept Cellular Pathol, Dublin 24, Ireland
[2] Adelaide & Meath Hosp, Dept Urol, Dublin 24, Ireland
[3] Adelaide & Meath Hosp, Dept Hematol, Dublin 24, Ireland
来源：
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2005年 / 13卷 / 04期
关键词：
bladder; lymphoma; CD30-positive anaplastic large-cell lymphoma;
D O I：
10.1177/106689690501300414
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Anaplastic large cell lymphoma (ALCL) is a T-cell lymphoma composed of large 14 pleomorphic CD30-positive cells. While systemic ALCL frequently involves extra-nodal sites, involvement of the Urinary bladder is extremely rare. We report a case of systemic ALCL presenting with bladder involvement. A 28-year-old man presented with hematuria, dysuria, and lower abdominal pain. Imaging revealed pelvic lymphadenopathy and a thickened bladder wall. Bladder biopsies showed diffuse infiltration of the lamina propria by large pleomorphic cells, with preservation of the overlying urothelium. Immunohistochemistry demonstrated cell membrane and Golgi region staining for CD30 and epithelial membrane antigen. This is the first documented instance of systemic ALCL presenting with bladder symptoms.
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收藏
页码：369 / 373
页数：5
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