An Overview on Plant Derived Phenolic Compounds and Their Role in Treatment and Management of Diabetes

被引：21
作者：
Deka, Himangshu [1 ]
Choudhury, Ananta [1 ,2 ]
Dey, Biplab Kumar [1 ]
机构：
[1] Assam Down Town Univ, Fac Pharmaceut Sci, Gauhati, Assam, India
[2] Assam Down Town Univ, Fac Pharmaceut Sci, Gauhati 781026, Assam, India
来源：
JOURNAL OF PHARMACOPUNCTURE | 2022年 / 25卷 / 03期
基金：
英国科研创新办公室;
关键词：
diabetes mellitus; secondary metabolites; phenolic acids; flavonoids; stilbenes; AMELIORATES HYPERGLYCEMIA; SIGNALING PATHWAYS; GLUCOSE-UPTAKE; ELLAGIC ACID; CAFFEIC ACID; MUSCLE-CELLS; GALLIC ACID; QUERCETIN; METABOLISM; ACTIVATION;
D O I：
10.3831/KPI.2022.25.3.199
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Objectives: In recent decades, the trend for treating diabetes mellitus (DM) has shifted toward alternative medicines that are obtained from plant sources. Existing literature sug-gests that phenolic compounds derived from plants possess promising health-promoting properties. This study aimed to discuss the role of plant-derived phenolic compounds in the effective treatment and management of diabetes.Methods: Information about plant secondary metabolites, phenolic compounds, and their role in the treatment and management of diabetes was collected from different data-bases, such as Pubmed, ScienceDirect, Scopus, and Google Scholar. Keywords like sec-ondary metabolites, phenolic compounds, simple phenol, flavonoids, lignans, stilbenes, and diabetes were searched. Research and review articles with relevant information were included in the study.Results: Anti-diabetic studies of the four major classes of phenolic compounds were in-cluded in this review. The plant-derived phenolic compounds were reported to have potent anti-diabetic activities. However, each class of phenolic compounds was found to behave differently according to various mechanisms.Conclusion: The obtained results suggest that phenolic compounds derived from natural sources display promising anti-diabetic activities. Based on the available information, it can be concluded that phenolic compounds obtained from various natural sources play key roles in the treatment and management of diabetes.
引用
收藏
页码：199 / 208
页数：10
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