Neutron capture autoradiography for a study on boron neutron capture therapy

被引:21
|
作者
Ogura, K
Yamazaki, A
Yanagie, H
Eriguchi, M
Lehmann, EH
Küehne, G
Bayon, G
Maruyama, K
Kobayashi, H
机构
[1] Nihon Univ, Coll Ind Technol, High Technol Res Ctr, Narashino, Chiba 2750005, Japan
[2] Univ Tokyo, Inst Med Sci, Dept Surg, Minato Ku, Tokyo 108, Japan
[3] Paul Scherrer Inst, Dept Spallat Neutron Source, CH-5232 Villigen, Switzerland
[4] CEN Saclay, CEA, SIREN, DRE,SRO, F-91191 Gif Sur Yvette, France
[5] Teikyo Univ, Sch Pharmaceut Sci, Sagamiko, Kanagawa 1990195, Japan
[6] Rikkyo Univ, Inst Atom Energy, Yokosuka, Kanagawa 24001, Japan
关键词
boron neutron capture therapy; neutron capture alpha-autoradiography; CR-39; cold neutron; thermal neutron; PEW etching solution;
D O I
10.1016/S1350-4487(01)00227-X
中图分类号
TL [原子能技术]; O571 [原子核物理学];
学科分类号
0827 ; 082701 ;
摘要
For the study on boron neutron capture therapy, CR-39 plastic track detectors attached with the whole-body sections of tumor bearing mice infused with B-10 were exposed to thermal and cold neutron beams. Neutron capture autoradiographic images obtained by the cold neutron irradiation were extremely superior in quality than that of the thermal neutron beams, which possibly are contaminated by the fast neutron component. The LET distributions of the neutron-induced particles suggested that the fast neutron component was considerably included in the thermal neutron beams used in this study. In addition, the quality of radiographic images obtained by PEW etching is compared with the images on CR-39 etched in a NaOH solution. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:555 / 558
页数:4
相关论文
共 50 条
  • [41] The Development of Boron Analysis and Imaging in Boron Neutron Capture Therapy (BNCT)
    Dai, Qi
    Yang, QiYao
    Bao, Xiaoyan
    Chen, Jiejian
    Han, Min
    Wei, Qichun
    MOLECULAR PHARMACEUTICS, 2022, 19 (02) : 363 - 377
  • [42] A Critical Assessment of Boron Target Compounds for Boron Neutron Capture Therapy
    M. Frederick Hawthorne
    Mark W. Lee
    Journal of Neuro-Oncology, 2003, 62 : 33 - 45
  • [43] Boron neutron capture therapy assisted by boron-conjugated nanoparticles
    Shogo Sumitani
    Yukio Nagasaki
    Polymer Journal, 2012, 44 : 522 - 530
  • [44] A critical assessment of boron target compounds for boron neutron capture therapy
    M. Frederick Hawthorne
    Mark W. Lee
    Journal of Neuro-Oncology, 2003, 62 (1-2) : 33 - 45
  • [45] Study of neutron production and moderation for sulfur neutron capture therapy
    Meng Peng
    Guo-Zhu He
    Qi-Wei Zhang
    Bin Shi
    Hong-Qing Tang
    Zu-Ying Zhou
    Nuclear Science and Techniques, 2019, 30 (01) : 56 - 63
  • [46] Boron neutron capture therapy assisted by boron-conjugated nanoparticles
    Sumitani, Shogo
    Nagasaki, Yukio
    POLYMER JOURNAL, 2012, 44 (06) : 522 - 530
  • [47] Study of neutron production and moderation for sulfur neutron capture therapy
    Meng Peng
    Guo-Zhu He
    Qi-Wei Zhang
    Bin Shi
    Hong-Qing Tang
    Zu-Ying Zhou
    Nuclear Science and Techniques, 2019, 30
  • [48] Study of neutron production and moderation for sulfur neutron capture therapy
    Peng, Meng
    He, Guo-Zhu
    Zhang, Qi-Wei
    Shi, Bin
    Tang, Hong-Qing
    Zhou, Zu-Ying
    NUCLEAR SCIENCE AND TECHNIQUES, 2019, 30 (01)
  • [49] Conceptual study of a compact accelerator-driven neutron source for radioisotope production, boron neutron capture therapy and fast neutron therapy
    Angelone, M
    Atzeni, S
    Rollet, S
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2002, 487 (03) : 585 - 594
  • [50] The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy
    Masunaga, Shin-ichiro
    Sakurai, Yoshinori
    Tanaka, Hiroki
    Tano, Keizo
    Suzuki, Minoru
    Kondo, Natsuko
    Narabayashi, Masaru
    Nakagawa, Yosuke
    Watanabe, Tsubasa
    Maruhashi, Akira
    Ono, Koji
    SPRINGERPLUS, 2014, 3 : 1 - 11