Neutron capture autoradiography for a study on boron neutron capture therapy

被引:22
作者
Ogura, K
Yamazaki, A
Yanagie, H
Eriguchi, M
Lehmann, EH
Küehne, G
Bayon, G
Maruyama, K
Kobayashi, H
机构
[1] Nihon Univ, Coll Ind Technol, High Technol Res Ctr, Narashino, Chiba 2750005, Japan
[2] Univ Tokyo, Inst Med Sci, Dept Surg, Minato Ku, Tokyo 108, Japan
[3] Paul Scherrer Inst, Dept Spallat Neutron Source, CH-5232 Villigen, Switzerland
[4] CEN Saclay, CEA, SIREN, DRE,SRO, F-91191 Gif Sur Yvette, France
[5] Teikyo Univ, Sch Pharmaceut Sci, Sagamiko, Kanagawa 1990195, Japan
[6] Rikkyo Univ, Inst Atom Energy, Yokosuka, Kanagawa 24001, Japan
关键词
boron neutron capture therapy; neutron capture alpha-autoradiography; CR-39; cold neutron; thermal neutron; PEW etching solution;
D O I
10.1016/S1350-4487(01)00227-X
中图分类号
TL [原子能技术]; O571 [原子核物理学];
学科分类号
0827 ; 082701 ;
摘要
For the study on boron neutron capture therapy, CR-39 plastic track detectors attached with the whole-body sections of tumor bearing mice infused with B-10 were exposed to thermal and cold neutron beams. Neutron capture autoradiographic images obtained by the cold neutron irradiation were extremely superior in quality than that of the thermal neutron beams, which possibly are contaminated by the fast neutron component. The LET distributions of the neutron-induced particles suggested that the fast neutron component was considerably included in the thermal neutron beams used in this study. In addition, the quality of radiographic images obtained by PEW etching is compared with the images on CR-39 etched in a NaOH solution. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:555 / 558
页数:4
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