Dietary modulation of paraoxonase-1 activity and concentration in humans

被引：1
|
作者：
Dalgard, C. [1 ]
机构：
[1] Univ So Denmark, Inst Publ Hlth Environm Med, Odense, Denmark
来源：
PARAOXNASES: THEIR ROLE IN DISEASE DEVELOPMENT AND XENOBIOTIC METABOLISM | 2008年 / 6卷
关键词：
diet; fruit and vegetables; pomegranate juice; oils; dietary fatty acids; postprandial effects; nutrient-gene interaction;
D O I：
10.1007/978-1-4020-6561-3_19
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Due to the assumed anti-atherogenic properties of PON1, it is of potential interest to identify pharmacological and environmental modulators of PON1 activity and concentration. Diet may be one of these environmental factors and this chapter focuses on dietary factors that may affect serum PON1 activity and concentration in humans. In general, the effect of most of the various dietary factors tested on enzyme activity is modest. However, a few studies indicate that the genetic variation in PON1 may contribute to individual variation in response to nutrient intake. Further studies including larger sample sizes are needed to clarify this important public health issue.
引用
收藏
页码：283 / 293
页数：11
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