Influence of electron density spatial distribution and X-ray beam quality during CT simulation on dose calculation accuracy

被引：18

作者：

Nobah, Ahmad ^{[1
]}

Moftah, Belal ^{[1
]}

Tomic, Nada ^{[2
]}

Devic, Slobodan ^{[2
]}

机构：

[1] King Faisal Specialist Hosp & Res Ctr, Dept Biomed Phys, Riyadh 11211, Saudi Arabia

[2] McGill Univ, Jewish Gen Hosp, Dept Radiat Oncol, Montreal, PQ H3T 1E2, Canada

来源：

JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS | 2011年 / 12卷 / 03期

关键词：

Monte Carlo dose calculations; heterogeneity corrections; TREATMENT PLANNING SYSTEM; RADIOTHERAPY; CALIBRATION; PHANTOM;

D O I：

10.1120/jacmp.v12i3.3432

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Impact of the various kVp settings used during computed tomography (CT) simulation that provides data for heterogeneity corrected dose distribution calculations in patients undergoing external beam radiotherapy with either high-energy photon or electron beams have been investigated. The change of the Hounsfield Unit (HU) values due to the influence of kVp settings and geometrical distribution of various tissue substitute materials has also been studied. The impact of various kVp settings and electron density (ED) distribution on the accuracy of dose calculation in high-energy photon beams was found to be well within 2%. In the case of dose distributions obtained with a commercially available Monte Carlo dose calculation algorithm for electron beams, differences of more than 10% were observed for different geometrical setups and kVp settings. Dose differences for the electron beams are relatively small at shallow depths but increase with depth around lower isodose values.

引用

页码：80 / 89

页数：10

共 11 条

[1] Dose calculations for external photon beams in radiotherapy [J].

Ahnesjö, A ;

Aspradakis, MM .

PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (11) :R99-R155

[2] Evaluation of a Monte Carlo Based Commercial Electron Beam Treatment Planning System [J].

Al Kafi, M. ;

Moftah, B. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 78 (03) :S844-S844

[3] AN ELECTRON-DENSITY CALIBRATION PHANTOM FOR CT-BASED TREATMENT PLANNING COMPUTERS [J].

CONSTANTINOU, C ;

HARRINGTON, JC ;

DEWERD, LA .

MEDICAL PHYSICS, 1992, 19 (02) :325-327

[4] Dosimetric impact of computed tomography calibration on a commercial treatment planning system for external radiation therapy [J].

Cozzi, L ;

Fogliata, A ;

Buffa, F ;

Bieri, S .

RADIOTHERAPY AND ONCOLOGY, 1998, 48 (03) :335-338

[5] Comparison of the Batho, ETAR and Monte Carlo dose calculation methods in CT based patient models [J].

du Plessis, FCP ;

Willemse, CA ;

Lötter, MG ;

Goedhals, L .

MEDICAL PHYSICS, 2001, 28 (04) :582-589

[6] CT number variations due to different image acquisition and reconstruction parameters: a thorax phantom study [J].

Groell, R ;

Rienmueller, R ;

Schaffler, GJ ;

Portugaller, HR ;

Graif, E ;

Willfurth, P .

COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, 2000, 24 (02) :53-58

[7] Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings [J].

Guan, HQ ;

Yin, FF ;

Kim, JH .

PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (17) :N223-N231

[8] Tolerance levels for quality assurance of electron density values generated from CT in radiotherapy treatment planning [J].

Kilby, W ;

Sage, J ;

Rabett, V .

PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (09) :1485-1492

[9]

MILLNER M R, 1979, Medical Physics (Woodbury), V6, P70, DOI 10.1118/1.594555

[10] Assessing the effect of electron density in photon dose calculations [J].

Seco, J ;

Evans, PM .

MEDICAL PHYSICS, 2006, 33 (02) :540-552

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