Cognitive functioning in a population-based sample of young adults with anxiety disorders

被引：33

作者：

Castaneda, A. E. ^{[1
,2
,3
]}

Suvisaari, J. ^{[1
,2
,4
]}

Marttunen, M. ^{[1
,2
,5
,6
]}

Perala, J. ^{[1
,2
]}

Saarni, S. I. ^{[1
,2
,6
]}

Aalto-Setala, T. ^{[1
,2
,7
]}

Lonnqvist, J. ^{[1
,2
,6
]}

Tuulio-Henriksson, A. ^{[1
,2
,3
]}

机构：

[1] Natl Inst Hlth & Welf, Dept Mental Hlth, Helsinki 00300, Finland

[2] Natl Inst Hlth & Welf, Subst Abuse Serv, Helsinki 00300, Finland

[3] Univ Helsinki, Dept Psychol, SF-00100 Helsinki, Finland

[4] Univ Tampere, Tampere Sch Publ Hlth, Dept Social Psychiat, FIN-33101 Tampere, Finland

[5] Univ Helsinki, Cent Hosp, Dept Adolescent Psychiat, Helsinki, Finland

[6] Univ Helsinki, Dept Psychiat, SF-00180 Helsinki, Finland

[7] Univ Helsinki, Cent Hosp, Dept Child Psychiat, Helsinki, Finland

来源：

EUROPEAN PSYCHIATRY | 2011年 / 26卷 / 06期

基金：

芬兰科学院;

关键词：

Anxiety disorder; Neuropsychology; Cognitive impairment; Young adult; General population; OBSESSIVE-COMPULSIVE DISORDER; POSTTRAUMATIC-STRESS-DISORDER; AGE-OF-ONSET; PANIC DISORDER; NEUROPSYCHOLOGICAL PROFILE; NEUROCOGNITIVE IMPAIRMENT; MENTAL-DISORDERS; SOCIAL PHOBIA; MEMORY; PERFORMANCE;

D O I：

10.1016/j.eurpsy.2009.11.006

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective. - Cognitive functioning in anxiety disorders has received little investigation, particularly among young adults and in non-clinical samples. The present study examined cognitive functioning in a population-based sample of young adults with anxiety disorders in comparison to healthy peers. Methods. - A population-based sample of 21-35-year-olds with a lifetime history of anxiety disorders (n = 75) and a random sample of healthy controls (n = 71) derived from the same population were compared in terms of performance in neuropsychological tests measuring verbal and visual short-term memory, verbal long-term memory, attention, psychomotor processing speed, and executive functioning. Results. - In general, young adults with anxiety disorders did not have major cognitive impairments when compared to healthy peers. When participants with anxiety disorder in remission were excluded, persons with current anxiety disorder scored lower in visual working memory tests. Current psychotropic medication use and low current psychosocial functioning associated with deficits in executive functioning, psychomotor processing speed, and visual short-term memory. Conclusion. - Lifetime history of anxiety disorders is not associated with cognitive impairment among young adults in the general population. However, among persons with anxiety disorders, current psychotropic medication use and low psychosocial functioning, indicating more severe symptoms, may associate with cognitive impairments. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：346 / 353

页数：8

共 69 条

[1] WISCONSIN CARD SORTING TEST-PERFORMANCE IN OBSESSIVE-COMPULSIVE DISORDER - NO EVIDENCE FOR INVOLVEMENT OF DORSOLATERAL PREFRONTAL CORTEX [J].