Lipid peroxidation: control of cell proliferation, cell differentiation and cell death

被引:120
作者
Barrera, Giuseppina [1 ]
Pizzimenti, Stefania [1 ]
Dianzani, Mario Umberto [1 ]
机构
[1] Univ Turin, Dipartimento Med & Oncol Sperimentale, Turin, Italy
关键词
lipid peroxidation; proliferation; differentiation; apoptosis;
D O I
10.1016/j.mam.2007.09.012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In recent years, it has become evident that lipid peroxidation is not only a mechanism for deterioration of alimentary oils and fats, but can occur even in living cells, both in pathological and physiological conditions. Through its aldehydic products, it can regulate several cellular processes, as proliferation, differentiation and apoptosis of normal and neoplastic cells. In this review we describe some recent findings obtained in these fields. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 8
页数:8
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