The two-component system CesRK controls the transcriptional induction of cell envelope-related genes in Listeria monomozenes in response to cell wall-acting antibiotics

被引：32

作者：

Gottschalk, Sanne ^{[1
]}

Bygebjerg-Hove, Iver ^{[1
]}

Bonde, Mette ^{[1
]}

Nielsen, Pia Kiil ^{[1
]}

Nguyen, Thanh Ha ^{[1
]}

Gravesen, Anne ^{[2
]}

Kallipolitis, Birgitte H. ^{[1
]}

机构：

[1] Univ So Denmark, Dept Biochem & Mol Biol, DK-5230 Odense, Denmark

[2] Univ Copenhagen, Dept Food Sci, Frederiksberg 1958 C, Denmark

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 13期

关键词：

D O I：

10.1128/JB.00015-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The two-component system CesRK of Listeria monocytogenes responds to cell wall-acting antibiotics. We show here that CesRK controls the transcription of several cell envelope-related genes. The CesRK-dependent induction of these genes may be viewed as an attempt by L. monocytogenes to protect itself against the damaging effects of cell wall-acting antibiotics.

引用

页码：4772 / 4776

页数：5

共 16 条

[1] THE VANZ GENE OF TN1546 FROM ENTEROCOCCUS-FAECIUM BM4147 CONFERS RESISTANCE TO TEICOPLANIN [J].

ARTHUR, M ;

DEPARDIEU, F ;

MOLINAS, C ;

REYNOLDS, P ;

COURVALIN, P .

GENE, 1995, 154 (01) :87-92

[2] Listeria monocytogenes surface proteins: from genome predictions to function [J].

Bierne, Helene ;

Cossart, Pascale .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2007, 71 (02) :377-+

[3] The LisRK signal transduction system determines the sensitivity of Listeria monocytogenes to nisin and cephalosporins [J].

Cotter, PD ;

Guinane, CM ;

Hill, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (09) :2784-2790

[4] Identification and disruption of lisRK, a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes [J].

Cotter, PD ;

Emerson, N ;

Gahan, CGM ;

Hill, C .

JOURNAL OF BACTERIOLOGY, 1999, 181 (21) :6840-6843

[5] pbp2229-mediated nisin resistance mechanism in Listeria monocytogenes confers cross-protection to class IIa bacteriocins and affects virulence gene expression [J].

Gravesen, A ;

Kallipolitis, B ;

Holmstrom, K ;

Hoiby, PE ;

Ramnath, M ;

Knochel, S .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 70 (03) :1669-1679

[6] Contribution of penicillin-binding protein homologs to antibiotic resistance, cell morphology, and virulence of Listeria monocytogenes EGDe [J].

Guinane, Caitriona M. ;

Cotter, Paul D. ;

Ross, R. Paul ;

Hill, Colin .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (08) :2824-2828

[7] CesRK, a two-component signal transduction system in Listeria monocytogenes, responds to the presence of cell wall-acting antibiotics and affects β-lactam resistance [J].

Kallipolitis, BH ;

Ingmer, H ;

Gahan, CG ;

Hill, C ;

Sogaard-Andersen, L .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (11) :3421-3429

[8]

Kallipolitis BH, 2001, FEMS MICROBIOL LETT, V204, P111, DOI 10.1016/S0378-1097(01)00386-X

[9] SEQUENCING AND ANALYSIS OF THE BACILLUS-SUBTILIS LYTRABC DIVERGON - A REGULATORY UNIT ENCOMPASSING THE STRUCTURAL GENES OF THE N-ACETYLMURAMOYL-L-ALANINE AMIDASE AND ITS MODIFIER [J].

LAZAREVIC, V ;

MARGOT, P ;

SOLDO, B ;

KARAMATA, D .

JOURNAL OF GENERAL MICROBIOLOGY, 1992, 138 :1949-1961

[10]

Poyart C, 1997, FEMS MICROBIOL LETT, V156, P193, DOI 10.1111/j.1574-6968.1997.tb12726.x

← 1 2 →