Bacterial symbiosis in arthropods and the control of disease transmission

被引：92
作者：
Beard, CB
Durvasula, RV
Richards, FF
机构：
[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA
[2] Yale Univ, Sch Med, New Haven, CT USA
来源：
EMERGING INFECTIOUS DISEASES | 1998年 / 4卷 / 04期
关键词：
D O I：
10.3201/eid0404.980408
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Bacterial symbionts may be used as vehicles for expressing foreign genes in arthropods. Expression of selected genes can render an arthropod incapable of transmitting a second microorganism that is pathogenic for humans and is an alternative approach to the control of arthropod-borne diseases. We discuss the rationale for this alternative approach, its potential applications and limitations, and the regulatory concerns that may arise from its use in interrupting disease transmission in humans and animals.
引用
收藏
页码：581 / 591
页数：11
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