Short Report: Tumor Necrosis Factor-α and Mortality in Patients Infected with Vibrio vulnificus

被引：5
作者：
Lee, Jun-Young
Kim, Dong-Min
Yun, Na Ra
Neupane, Ganesh Prasad
Jung, Sook-In [1 ]
Park, Kyung-Hwa [1 ]
Jang, Hee Chang [1 ]
Lee, Chang Seop [2 ]
Lee, Sun Hee [3 ]
机构：
[1] Chonnam Natl Univ Hosp, Dept Infect Dis, Kwangju, South Korea
[2] Chonbuk Natl Univ, Sch Med, Dept Internal Med, Jeonju, South Korea
[3] Pusan Natl Univ, Coll Med, Dept Internal Med, Pusan 609735, South Korea
来源：
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2011年 / 84卷 / 03期
关键词：
ASSOCIATION; SERUM; IRON;
D O I：
10.4269/ajtmh.2011.10-0310
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Serum tumor necrosis factor-alpha (TNF-alpha) was evaluated in Vibrio vulnificus-infected patients at admission. The median TNF-alpha concentration in the non-survivor group was determined to be 261.0 pg/mL, in contrast to 69.5 pg/mL in the survivor group (P = 0.001). Hence, serum TNF-alpha concentration may potentially be an early predictor of the mortality in patients with Vibrio septicemia.
引用
收藏
页码：426 / 428
页数：3
相关论文
共 12 条
[1]   HEMOCHROMATOSIS, IRON, AND SEPTICEMIA CAUSED BY VIBRIO-VULNIFICUS [J].
BULLEN, JJ ;
SPALDING, PB ;
WARD, CG ;
GUTTERIDGE, JMC .
ARCHIVES OF INTERNAL MEDICINE, 1991, 151 (08) :1606-1609
[2]   A role for tumor necrosis factor-alpha in the increased mortality associated with Vibrio vulnificus infection in the presence of hepatic dysfunction [J].
Espat, NJ ;
Auffenberg, T ;
Abouhamze, A ;
Baumhofer, J ;
Moldawer, LL ;
Howard, RJ .
ANNALS OF SURGERY, 1996, 223 (04) :428-433
[3]   The epidemiology of Vibrio infections in Florida, 1981-1993 [J].
Hlady, WG ;
Klontz, KC .
JOURNAL OF INFECTIOUS DISEASES, 1996, 173 (05) :1176-1183
[4]   Mechanism of high susceptibility of iron-overloaded mouse to Vibrio vulnificus infection [J].
Hor, LI ;
Chang, YK ;
Chang, CC ;
Lei, HY ;
Ou, JT .
MICROBIOLOGY AND IMMUNOLOGY, 2000, 44 (11) :871-878
[5]   A serosurvey of Orientia tsutsugamushi from patients with scrub typhus [J].
Kim, D. M. ;
Lee, Y. -M. ;
Back, J. -H. ;
Yang, T. Y. ;
Lee, J. H. ;
Song, H. -J. ;
Shim, S. -K. ;
Hwang, K. -J. ;
Park, M. -Y. .
CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (05) :447-451
[6]   In vitro efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus [J].
Kim, DM ;
Lym, Y ;
Jang, SJ ;
Han, H ;
Kim, YG ;
Chung, CH ;
Hong, SP .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (08) :3489-3491
[7]   Comparison of conventional, nested, and real-time PCR assays for rapid and accurate detection of Vibrio vulnificus [J].
Kim, Hyong Sun ;
Kim, Dong-Min ;
Neupane, Ganesh Prasad ;
Lee, Yu-mi ;
Yang, Nam-Woong ;
Jang, Sook Jin ;
Jung, Sook-In ;
Park, Kyung-Hwa ;
Park, Hae-Ryoung ;
Lee, Chang Seop ;
Lee, Sun Hee .
JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (09) :2992-2998
[8]   The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock:: Association with serum lactate and inflammatory cytokine levels [J].
Kumar, A ;
Haery, C ;
Paladugu, B ;
Kumar, A ;
Symeoneides, S ;
Taiberg, L ;
Osman, J ;
Trenholme, G ;
Opal, SM ;
Goldfarb, R ;
Parrillo, JE .
JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (02) :251-258
[9]   Release of tumor necrosis factor alpha in response to Vibrio vulnificus capsular polysaccharide in in vivo and in vitro models [J].
Powell, JL ;
Wright, AC ;
Wasserman, SS ;
Hone, DM ;
Morris, JG .
INFECTION AND IMMUNITY, 1997, 65 (09) :3713-3718
[10]  
Shin SH, 2002, FEMS IMMUNOL MED MIC, V33, P133, DOI 10.1111/j.1574-695X.2002.tb00582.x
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