Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts

被引：0

作者：

Mancuso, Raffaella ^{[1
]}

Amuso, Roberta ^{[1
]}

Armentano, Biagio ^{[2
]}

Grasso, Giuseppe ^{[1
]}

Rago, Vittoria ^{[2
]}

Cappello, Anna Rita ^{[2
]}

Galiano, Francesco ^{[3
]}

Figoli, Alberto ^{[3
]}

De Luca, Giorgio ^{[3
]}

Hoinkis, Jan ^{[4
]}

Gabriele, Bartolo ^{[1
]}

机构：

[1] Univ Calabria, Dept Chem & Chem Technol, Via P Bucci 12-C, I-87036 Arcavacata Di Rende, Italy

[2] Univ Calabria, Dept Pharm & Hlth & Nutrit Sci, I-87036 Arcavacata Di Rende, Italy

[3] CNR, Inst Membrane Technol, Via P Bucci 17-C, I-87036 Arcavacata Di Rende, Italy

[4] Karlsruhe Univ Appl Sci, Inst Appl Res, Moltkestr 30, D-76133 Karlsruhe, Germany

来源：

CHEMPLUSCHEM | 2017年 / 82卷 / 10期

基金：

欧盟地平线“2020”;

关键词：

antifouling membranes; antimicrobial polymers; organic synthesis; polymerizable quaternary ammonium salts; quaternary ammonium salts; QUATERNARY AMMONIUM; SURFACE MODIFICATION; FIBROUS MEMBRANES;

D O I：

10.1002/cplu.201700194

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This study reports an efficient and practical synthetic approach for the synthesis of a particularly important class of polymerizable quaternary ammonium salts (PQASs), that is, acryloxyalkyltriethylammonium bromides (AATEABs), which may find application as antimicrobial coatings for commercial membranes with antifouling and anti-biofouling properties, to be used for wastewater treatment. The synthetic method is based on a simple two-step procedure from commercially available substrates, entirely carried out under air and without any need for chromatographic purification. All the newly synthesized AATEABs were tested for their antimicrobial activity, and the results showed that AATEABs bearing an alkyl chain of 11 and particularly 12 carbon atoms possessed significant activity against Gram positive bacteria and yeast strains.

引用

页码：1235 / 1244

页数：10

共 33 条

[1] [Anonymous], 2018, Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts, V3
[2] [Anonymous], 2014, POLYM MAT ANTIMICROB
[3] [Anonymous], 2008, Approved standard M27-A. A National Committee for Clinical Laboratory Standards
[4] Synthesis and antibacterial activities of new quaternary ammonium monomers
Ayfer, B
Dizman, B
Elasri, MO
Mathias, LJ
Avci, D
[J]. DESIGNED MONOMERS AND POLYMERS, 2005, 8 (05) : 437 - 451
[5] Methods for in vitro evaluating antimicrobial activity: A review
Balouiri, Mounyr
Sadiki, Moulay
Koraichi Ibnsouda, Saad
[J]. JOURNAL OF PHARMACEUTICAL ANALYSIS, 2016, 6 (02) : 71 - 79
[6] BAUER AW, 1966, AM J CLIN PATHOL, V45, P493
[7] Benson H.J, 2002, Microbiological Applications: Laboratory Manual in General Microbiology, V8th
[8] Benson H. J., 1998, MICROBIOLOGICAL APPL, P139
[9] Fabrication of transparent quaternized PVA/silver nanocomposite hydrogel and its evaluation as an antimicrobial patch for wound care systems
Bhowmick, Sirsendu
Mohanty, Sujata
Koul, Veena
[J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2016, 27 (11)
[10] Clinical and Laboratory Standards Institute, 2012, M07A9 CLIN LAB STAND

← 1 2 3 4 →