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Stem-cell transplantation in patients with germ cell tumors
被引:0
|作者:
Linkesch, W
[1
]
机构:
[1] Graz Univ, Med Klin, Klin Abt Hamatol, A-8036 Graz, Austria
关键词:
germ cell tumor;
stem-cell transplantation;
high-dose chemotherapy;
D O I:
暂无
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
High dose chemotherapy (HDCT) with autologous stem cell transplantation in patients with relapsed or refractory non-seminomatous germ cell tumors seems to be the only therapeutic option with curative intention. Evaluation of a scored risk profile before HDCT might significantly support the precise estimation of results after HDCT. Patients with a negative or low score could achieve long-lasting complete remissions or might be cured, whereas patients with absolutely refractory disease do not benefit from HDCT. Ongoing prospective randomised trials in Europe and USA comparing standardtherapy with KDCT will hopefully contribute to the right therapeutic decision in the future.
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页码:30 / 32
页数:3
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