Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis (vol 69, pg 298, 2007)

被引：0
|
作者：
Chellappan, S.
机构：
来源：
CHEMICAL BIOLOGY & DRUG DESIGN | 2007年 / 69卷 / 06期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：455 / 455
页数：1
相关论文
共 19 条
  • [1] Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis
    Chellappan, Sripriya
    Reddy, G. S. Kiran Kumar
    Ali, Akbar
    Nalam, Madhavi N. L.
    Anjum, Saima Ghafoor
    Cao, Hong
    Kairys, Visvaldas
    Fernandes, Miguel X.
    Altman, Michael D.
    Tidor, Bruce
    Rana, Tariq M.
    Schiffer, Celia A.
    Gilson, Michael K.
    CHEMICAL BIOLOGY & DRUG DESIGN, 2007, 69 (05) : 298 - 313
  • [2] Toward the Design of Mutation-Resistant Enzyme Inhibitors: Further Evaluation of the Substrate Envelope Hypothesis
    Kairys, Visvaldas
    Gilson, Michael K.
    Lather, Viney
    Schiffer, Celia A.
    Fernandes, Miguel X.
    CHEMICAL BIOLOGY & DRUG DESIGN, 2009, 74 (03) : 234 - 245
  • [3] Designing a combinatorial library of mutation-resistant HIV protease inhibitors.
    Chellappan, S
    Fernandes, MX
    Gilson, MK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 228 : U521 - U521
  • [4] Evaluation of the substrate envelope hypothesis for inhibitors of HIV-1 protease
    Chellappan, Sripriya
    Kairys, Visvaldas
    Fernandes, Miguel X.
    Schiffer, Celia
    Gilson, Michael K.
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2007, 68 (02) : 561 - 567
  • [5] Computational design of mutation-resistant HIV-1 protease inhibitor libraries.
    Chellappan, S
    Gilson, MK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U804 - U804
  • [6] Screening Novel HIV-1 Protease Inhibitors Based on the Substrate Envelope Hypothesis
    Miao Youpan
    Li Aixiu
    Liu Tao
    Wu Kezhu
    Ma Yi
    ACTA CHIMICA SINICA, 2009, 67 (10) : 1098 - 1102
  • [7] Positional Adaptability in the Design of Mutation-Resistant Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors: A Supramolecular Perspective
    Bruccoleri, Aldo
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2013, 29 (01) : 4 - 12
  • [8] Substrate envelope based design of new HIV-1 protease inhibitors active against drug-resistant HIV-1
    Ali, Akbar
    Reddy, G. S. Kiran Kumar
    Nalam, Madhavi N. L.
    Anjum, Saima G.
    Cao, Hong
    Altman, Michael D.
    Tidor, Bruce
    Rana, Tariq M.
    Schiffer, Celia A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [9] Substrate envelope based design of potent HIV-1 protease inhibitors resilient to resistance
    Nalam, M. N. L.
    Ali, A.
    Reddy, G. S. K. K.
    Anjum, S. G.
    Rana, T. M.
    Schiffer, C. A.
    ANTIVIRAL THERAPY, 2010, 15 : A15 - A15
  • [10] HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants
    Altman, Michael D.
    Ali, Akbar
    Reddy, G. S. Kiran Kumar
    Nalam, Madhavi N. L.
    Anjum, Saima Ghafoor
    Cao, Hong
    Chellappan, Sripriya
    Kairys, Visvalclas
    Fernandes, Miguel X.
    Gilson, Michael K.
    Schiffer, Celia A.
    Rana, Tariq M.
    Tidor, Bruce
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (19) : 6099 - 6113
12