An umpolung strategy for intermolecular [2+2+1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles

被引：2

作者：

Basavaiah, Deevi ^{[1
]}

Golime, Gangadhararao ^{[1
]}

Banoth, Shivalal ^{[1
]}

Todeti, Saidulu ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, India

来源：

CHEMICAL SCIENCE | 2022年 / 13卷 / 27期

关键词：

BAYLIS-HILLMAN REACTION; PAUSON-KHAND; CARBONYLATIVE CYCLOADDITION; ALKYNES; 1,3-DITHIANES; ANNULATION; REACTIVITY; CHEMISTRY;

D O I：

10.1039/d2sc00046f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have described the first example of an umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition between two aryl aldehydes and a nitrile under the influence of TMSOTf that proceeds through the formation of N-C, O-C and C-C bonds providing a simple synthetic protocol for obtaining 2,4,5-trisubstituted oxazoles.

引用

收藏

页码：8080 / 8087

页数：8

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