Chitosan-Halloysite Hydrogel Drug Delivery System

被引：0

作者：

Luo, Yangyang ^{[1
]}

Mills, David K. ^{[2
]}

机构：

[1] Louisiana Tech Univ, Mol Sci & Nanotechnol, 818 Nelson Av, Ruston, LA 71270 USA

[2] Louisiana Tech Univ, Biomed Engn, 818 Nelson Av, Ruston, LA 71270 USA

来源：

2016 32ND SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE (SBEC) | 2016年

关键词：

HNTs; chitosan; drug release;

D O I：

10.1109/SBEC.2016.55

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In this study, halloysite nanotubes (HNTs) were used to reinforce chitosan hydrogels, and built a biocompatible, biodegradable and sustained drug release system. The biodegradability, stretchability, and surface structure of the chitosan-HNTs hydrogels were studied. Gentamicin was selected as drug release model. Escherichia coli was used to estimate drug efficacy. Results indicate that HNTs significantly improved the gels' mechanical properties while, permitting an extended period of drug release, and without a negative affect on drug efficacy.

引用

页码：76 / 77

页数：2