Cross-Axis projection error in optically pumped magnetometers and its implication for magnetoencephalography systems

被引:75
作者
Borna, Amir [1 ]
Iivanainen, Joonas [1 ]
Carter, Tony R. [1 ]
McKay, Jim [2 ]
Taulu, Samu [3 ]
Stephen, Julia [4 ]
Schwindt, Peter D. D. [1 ]
机构
[1] Sandia Natl Labs, 1515 Eubank Blvd SE, Albuquerque, NM 87123 USA
[2] Candoo Syst Inc, Port Coquitlam, BC V3C 5M2, Canada
[3] Univ Washington, Seattle, WA 98195 USA
[4] Mind Res Network, Albuquerque, NM 87106 USA
基金
美国国家卫生研究院;
关键词
Cross-axis projection error; OPM; MEG; Source localization; OPM-MEG; Magnetoencephalography; CAPE; ATOMIC MAGNETOMETER; PERFORMANCE; OPERATION; FIELD;
D O I
10.1016/j.neuroimage.2021.118818
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Optically pumped magnetometers (OPMs) developed for magnetoencephalography (MEG) typically operate in the spin-exchange-relaxation-free (SERF) regime and measure a magnetic field component perpendicular to the propagation axis of the optical-pumping photons. The most common type of OPM for MEG employs alkali atoms, e.g. Rb-87, as the sensing element and one or more lasers for preparation and interrogation of the magnetically sensitive states of the alkali atoms ensemble. The sensitivity of the OPM can be greatly enhanced by operating it in the SERF regime, where the alkali atoms' spin exchange rate is much faster than the Larmor precession frequency. The SERF regime accommodates remnant static magnetic fields up to +/- 5 nT. However, in the presented work, through simulation and experiment, we demonstrate that multi-axis magnetic signals in the presence of small remnant static magnetic fields, not violating the SERF criteria, can introduce significant error terms in OPM's output signal. We call these deterministic errors cross-axis projection errors (CAPE), where magnetic field components of the MEG signal perpendicular to the nominal sensing axis contribute to the OPM signal giving rise to substantial amplitude and phase errors. Furthermore, through simulation, we have discovered that CAPE can degrade localization and calibration accuracy of OPM-based magnetoencephalography (OPM-MEG) systems.
引用
收藏
页数:10
相关论文
共 31 条
[1]   Non-Invasive Functional-Brain-Imaging with an OPM-based Magnetoencephalography System [J].
Borna, Amir ;
Carter, Tony R. ;
Colombo, Anthony P. ;
Jau, Yuan-Yu ;
McKay, Jim ;
Weisend, Michael ;
Taulu, Samu ;
Stephen, Julia M. ;
Schwindt, Peter D. D. .
PLOS ONE, 2020, 15 (01)
[2]   A 20-channel magnetoencephalography system based on optically pumped magnetometers [J].
Borna, Amir ;
Carter, Tony R. ;
Goldberg, Josh D. ;
Colombo, Anthony P. ;
Jau, Yuan-Yu ;
Berry, Christopher ;
Mckay, Jim ;
Stephen, Julia ;
Weisend, Michael ;
Schwindt, Peter D. D. .
PHYSICS IN MEDICINE AND BIOLOGY, 2017, 62 (23) :8909-8923
[3]   Moving magnetoencephalography towards real-world applications with a wearable system [J].
Boto, Elena ;
Holmes, Niall ;
Leggett, James ;
Roberts, Gillian ;
Shah, Vishal ;
Meyer, Sofie S. ;
Munoz, Leonardo Duque ;
Mullinger, Karen J. ;
Tierney, Tim M. ;
Bestmann, Sven ;
Barnes, Gareth R. ;
Bowtell, Richard ;
Brookes, Matthew J. .
NATURE, 2018, 555 (7698) :657-+
[4]   On the Potential of a New Generation of Magnetometers for MEG: A Beamformer Simulation Study [J].
Boto, Elena ;
Bowtell, Richard ;
Kruger, Peter ;
Fromhold, T. Mark ;
Morris, Peter G. ;
Meyer, Sofie S. ;
Barnes, Gareth R. ;
Brookes, Matthew J. .
PLOS ONE, 2016, 11 (08)
[5]   EXPERIMENTAL STUDY OF ZEEMAN LIGHT SHIFTS IN WEAK MAGNETIC-FIELDS [J].
COHENTANNOUDJI, C ;
DUPONTRO.J .
PHYSICAL REVIEW A-GENERAL PHYSICS, 1972, 5 (02) :968-+
[6]   VARIOUS LEVEL CROSSING RESONANCES ON ATOMS PUMPED OPTICALLY IN ZERO FIELD .1. THEORY [J].
COHENTANNOUDJI, C ;
DUPONTRO.J ;
HAROCHE, S ;
LALOE, F .
REVUE DE PHYSIQUE APPLIQUEE, 1970, 5 (01) :95-+
[7]   Four-channel optically pumped atomic magnetometer for magnetoencephalography [J].
Colombo, Anthony P. ;
Carter, Tony R. ;
Borna, Amir ;
Jau, Yuan-Yu ;
Johnson, Cort N. ;
Dagel, Amber L. ;
Schwindt, Peter D. D. .
OPTICS EXPRESS, 2016, 24 (14) :15403-15416
[8]   A high-sensitivity laser-pumped Mx magnetometer [J].
Groeger, S ;
Bison, G ;
Schenker, JL ;
Wynands, R ;
Weis, A .
EUROPEAN PHYSICAL JOURNAL D, 2006, 38 (02) :239-247
[9]   MAGNETOENCEPHALOGRAPHY - THEORY, INSTRUMENTATION, AND APPLICATIONS TO NONINVASIVE STUDIES OF THE WORKING HUMAN BRAIN [J].
HAMALAINEN, M ;
HARI, R ;
ILMONIEMI, RJ ;
KNUUTILA, J ;
LOUNASMAA, OV .
REVIEWS OF MODERN PHYSICS, 1993, 65 (02) :413-497
[10]  
Happer W., 2010, OPTICALLY PUMPED ATO