The preparation of glutathione-capped CdTe quantum dots and their use in imaging of cells

被引:44
作者
Xue, Mei [1 ]
Wang, Xu [1 ]
Wang, Hui [1 ]
Tang, Bo [1 ]
机构
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci,Minist Educ, Key Lab Mol & Nano Probes,Shandong Prov Key Lab C, Engn Res Ctr Pesticide & Med Intermediate Clean P, Jinan 250014, Peoples R China
基金
中国国家自然科学基金; 国家杰出青年科学基金;
关键词
CdTe; Quantum dots; Glutathione; Fluorescence; Cell imaging; CDS NANOCRYSTALS; AQUEOUS-PHASE; LUMINESCENT; WATER; PHOTOLUMINESCENCE; NANOPARTICLES; CYTOTOXICITY; TEMPERATURE; ACID;
D O I
10.1016/j.talanta.2010.11.064
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In this paper, different sizes of glutathione-capped CdTe (GSH/CdTe) quantum dots (QDs) have been prepared directly in aqueous solution. The QDs have tunable fluorescence in the range of 510-670 nm, and they also have high photoluminescence quantum yield (PLQY) without any postpreparative treatment. Furthermore, the QDs have strong resistance to photobleaching, and they also have to be considered as cytocompatible. In addition, for the first time, folic acid was covalently conjugated to the GSH/CdTe QDs for imaging of cancer cells, demonstrating their potentially broad application as biolabels. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:1680 / 1686
页数:7
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