Fever of unknown origin in HIV/AIDS patients

被引:28
作者
Hot, Arnaud [1 ]
Schmulewitz, Laura [1 ]
Viard, Jean-Paul [1 ]
Lortholary, Olivier [1 ,2 ]
机构
[1] Univ Paris 05, Hop Necker Enfants Malad, Ctr Infectiol Necker Pasteur, Serv Malad Infect & Trop, F-75743 Paris 15, France
[2] Inst Pasteur, CNRS, URA 3012, Ctr Natl Reference Mycol & Antifong, F-75724 Paris, France
关键词
D O I
10.1016/j.idc.2007.08.003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Fever of unknown or uncertain origin (FUO) constitutes a common clinical challenge in patients infected with HIV. It is usually caused by disseminated opportunistic infection, and the relative frequency of each cause of FUO is influenced by multiple factors including CD4 count, geographic setting, and local prevalences of infectious agents, which may provide clues to the diagnosis. Infections presenting as FUO in the HIV population occur most often in the late stages of the disease and high diagnostic suspicion for mycobacterial disease should be maintained when evaluating these patients, particularly in areas of high prevalence. This article discusses the causes, diagnosis, and treatment of FUO in HIV-infected individuals.
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页码:1013 / +
页数:21
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