Transcriptional regulation of activity-dependent genes by birdsong

被引:3
作者
Velho, Tarciso A. F. [1 ]
Mello, Claudio V. [1 ]
机构
[1] Oregon Hlth & Sci Univ, Inst Neurol Sci, 505 NW 185th Ave, Beaverton, OR 97006 USA
来源
TRANSCRIPTIONAL REGULATION BY NEURONAL ACTIVITY: TO THE NUCLEUS AND BACK | 2008年
关键词
D O I
10.1007/978-0-387-73609-9_1
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Birdsong is a natural learned behavior used extensively for vocal communication and controlled by a well-characterized set of discrete brain areas in songbirds. The acts of hearing and producing birdsong lead to robust transcriptional regulation of expression of activity-dependent genes in auditory and vocal control areas respectively. Therefore, birdsong provides an ideal paradigm to study transcription regulation by a natural learned stimulus in the brain of awake behaving animals. In this chapter we first discuss briefly some basic aspects of birdsong neurobiology, focusing on the substrates for perceptual and motor aspects of vocal communication in songbirds. We then discuss our current knowledge of the influence of stimulus type, behavioral condition and context on transcriptional regulation by song; the mechanisms regulating induced gene expression in song-encoding neurons; and the possible functional significance of the transcriptional response to song in auditory and song control areas of the songbird brain.
引用
收藏
页码:3 / +
页数:8
相关论文
共 143 条
[1]   SEXUAL DIMORPHISMS IN THE NEURAL VOCAL CONTROL-SYSTEM IN SONG BIRDS - ONTOGENY AND PHYLOGENY [J].
ARNOLD, AP ;
BOTTJER, SW ;
BRENOWITZ, EA ;
NORDEEN, EJ ;
NORDEEN, KW .
BRAIN BEHAVIOR AND EVOLUTION, 1986, 28 (1-3) :22-31
[2]   EFFECTS OF ANDROGENS ON VOLUMES OF SEXUALLY DIMORPHIC BRAIN-REGIONS IN THE ZEBRA FINCH [J].
ARNOLD, AP .
BRAIN RESEARCH, 1980, 185 (02) :441-444
[3]  
ASTONJONES G, 1981, J NEUROSCI, V1, P887
[4]  
ASTONJONES G, 1981, J NEUROSCI, V1, P876
[5]   Immediate early gene expression following exposure to acoustic and visual components of courtship in zebra finches [J].
Avey, MT ;
Phillmore, LS ;
MacDougall-Shackleton, SA .
BEHAVIOURAL BRAIN RESEARCH, 2005, 165 (02) :247-253
[6]   Neuronal calcium signaling [J].
Berridge, MJ .
NEURON, 1998, 21 (01) :13-26
[7]   Localized neuronal activation in the zebra finch brain is related to the strength of song learning [J].
Bolhuis, JJ ;
Zijlstra, GGO ;
den Boer-Visser, AM ;
Van der Zee, EA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (05) :2282-2285
[8]  
BONKE BA, 1979, CELL TISSUE RES, V200, P101
[9]   FOREBRAIN LESIONS DISRUPT DEVELOPMENT BUT NOT MAINTENANCE OF SONG IN PASSERINE BIRDS [J].
BOTTJER, SW ;
MIESNER, EA ;
ARNOLD, AP .
SCIENCE, 1984, 224 (4651) :901-903
[10]   THE DISTRIBUTION OF TYROSINE-HYDROXYLASE IMMUNOREACTIVITY IN THE BRAINS OF MALE AND FEMALE ZEBRA FINCHES [J].
BOTTJER, SW .
JOURNAL OF NEUROBIOLOGY, 1993, 24 (01) :51-69