Green Tea and Cancer Prevention

被引：122
作者：
Yang, Chung S. [1 ]
Wang, Xin [1 ]
机构：
[1] Rutgers State Univ, Ernest Mario Sch Pharm, Dept Biol Chem, Piscataway, NJ 08854 USA
来源：
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 2010年 / 62卷 / 07期
关键词：
GROWTH-FACTOR RECEPTOR; INDUCED LUNG TUMORIGENESIS; PROSTATE CARCINOMA-CELLS; (-)-EPIGALLOCATECHIN GALLATE; A/J MICE; BLACK TEA; POLYPHENOL (-)-EPIGALLOCATECHIN-3-GALLATE; BREAST-CANCER; SIGNALING PATHWAYS; COLORECTAL-CANCER;
D O I：
10.1080/01635581.2010.509536
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Extracts of green tea and green tea polyphenols have exhibited inhibitory effects against the formation and development of tumors at different organ sites in animals. These include animal models for skin, lung, oral cavity, esophagus, stomach, intestine, colon, liver, pancreas, bladder, mammary gland, and prostate cancers. In addition to suppressing cell proliferation, promoting apoptosis, and modulating signaling transduction, green tea polyphenols, especially (-)-epigallocatechin-3-gallate, also inhibit cell invasion, angiogenesis, and metastasis. This article reviews data on the cancer preventive activities of green tea polyphenols, possible mechanisms involved, and the relationship between green tea consumption and human cancer risk.
引用
收藏
页码：931 / 937
页数：7
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