310-helix stabilization via side-chain salt bridges

被引：0
|
作者：
Yokum, TS [1 ]
Bursavich, MG [1 ]
Gauthier, T [1 ]
Hammer, RP [1 ]
McLaughlin, ML [1 ]
机构：
[1] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA
来源：
CHEMICAL COMMUNICATIONS | 1998年 / 17期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Decapeptides, Sb-10 (H-Api-Aib-Aib-Glu-Aib-Aib-Glu-Aib-Aib-Api-NH2) and Ipi-10 (H-Api-Aib-Aib-Lys-Aib-Aib-Lys-Aib-Aib-Api-NH2), where Aib is alpha-aminoisobutyric acid and Api is 4-aminopiperidine-4-carboxylic acid, are designed to be amphipathic as 3(10)-helices; Sb-10 is the first example of a 3(10)-helical peptide stabilized by side-chain salt bridging or ion pairing.
引用
收藏
页码：1801 / 1802
页数：2
相关论文
共 50 条
  • [21] Enhancement of α-Helix Mimicry by an α/β-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array
    Johnson, Lisa M.
    Mortenson, David E.
    Yun, Hyun Gi
    Horne, W. Seth
    Ketas, Thomas J.
    Lu, Min
    Moore, John P.
    Gellman, Samuel H.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (17) : 7317 - 7320
  • [22] Sculpting the β-peptide foldamer H12 helix via a designed side-chain shape
    Hetenyi, Anasztazia
    Szakonyi, Zsolt
    Mandity, Istvan M.
    Szolnoki, Eva
    Toth, Gabor K.
    Martinek, Tamas A.
    Fueloep, Ferenc
    CHEMICAL COMMUNICATIONS, 2009, (02) : 177 - 179
  • [23] SIDE-CHAIN INTERACTIONS CONTROLLING ALPHA-HELIX STABILITY
    BALDWIN, RL
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1987, : 192 - 192
  • [24] THE DEPENDENCE OF ALPHA-HELIX FORMATION ON SIDE-CHAIN STRUCTURE
    CHARTON, M
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 202 : 37 - BIOL
  • [25] Cooperative helix stabilization by complex Arg-Glu salt bridges
    Olson, CA
    Spek, EJ
    Shi, ZS
    Vologodskii, A
    Kallenbach, NR
    PROTEINS-STRUCTURE FUNCTION AND GENETICS, 2001, 44 (02): : 123 - 132
  • [26] Gas phase formation of a 310-helix in a three-residue peptide chain:: Role of side chain-backbone interactions as evidenced by IR-UV double resonance experiments
    Chin, W
    Piuzzi, F
    Dognon, JP
    Dimicoli, L
    Tardivel, B
    Mons, M
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (34) : 11900 - 11901
  • [27] Conformational studies of Aib-rich peptides containing lactam-bridged side chains: Evidence of 310-helix formation
    Schievano, E
    Pagano, K
    Mammi, S
    Peggion, E
    BIOPOLYMERS, 2005, 80 (2-3) : 294 - 302
  • [28] LINEAR OLIGOPEPTIDES .225. CRITICAL MAIN-CHAIN LENGTH FOR CONFORMATIONAL CONVERSION FROM 310-HELIX TO ALPHA-HELIX IN POLYPEPTIDES
    PAVONE, V
    BENEDETTI, E
    DIBLASIO, B
    PEDONE, C
    SANTINI, A
    BAVOSO, A
    TONIOLO, C
    CRISMA, M
    SARTORE, L
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1990, 7 (06): : 1321 - 1331
  • [29] Peptide ligation via side-chain auxiliary
    Lutsky, Marina-Yamit
    Nepomniaschiy, Natalia
    Brik, Ashraf
    CHEMICAL COMMUNICATIONS, 2008, (10) : 1229 - 1231
  • [30] EFFECT OF SIDE-CHAIN CHIRALITY ON PEPTIDE HELIX TYPE AND SCREW SENSE
    Guryanov, I.
    Peggion, C.
    Formaggio, F.
    Lakhani, A.
    Keiderling, T. A.
    Toniolo, C.
    BIOPOLYMERS, 2009, 92 (04) : 360 - 360
12345