A novel ratiometric fluorescent probe for selective and sensitive detection of Cu2+ in complete aqueous solution

被引：58

作者：

Zhu, Dongjian ^{[1
]}

Ren, Aishan ^{[1
]}

He, Xingcun ^{[1
]}

Luo, Yanghe ^{[1
]}

Duan, Zhenhua ^{[1
]}

Yan, Xiaowei ^{[1
]}

Xiong, Yuhao ^{[1
]}

Zhong, Xing ^{[1
]}

机构：

[1] Hezhou Univ, Coll Food & Bioengn, Res Inst Food Sci & Engn Technol, Hezhou 542899, Peoples R China

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 252卷

基金：

中国国家自然科学基金;

关键词：

Copper ion; Ratiometric; Fluorescent probe; Hemicyanine; LIVING CELLS; FUNCTIONAL-GROUPS; CANCER-CELLS; COPPER; IONS; FRET; CHEMODOSIMETER; SENSOR; PLATFORM; TISSUES;

D O I：

10.1016/j.snb.2017.05.141

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel hemicyanine-based ratiometric fluorescent probe 3 for Cu2+ was described. The probe exhibited fluorescence emission at 448nm. Upon addition of Cu2+, the emission at 448nm quenched and simultaneously generated a significant bathochromic shift of the emission maximum to 503 nm due to the Cu2+-triggered hydrolysis reaction of the picolinate moiety. Thus, a singl-excitation, dual-emission ratiometric measurement with a large red shift in emission (triangle 55 nm) and remarkable changes in the ratio (F-503nm/F-448nm) of the emission intensity (R/R-o up to 22-fold) could be established. Moreover, the probe exhibited a large Stokes shift, high sensitivity (detection limit of 1.1 nM), and high selectivity for Cu2+ over other metal ions in complete aqueous solution. (C)2017 Elsevier B.V. All rights reserved.

引用

页码：134 / 141

页数：8

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