THE CFTR TRAFFICKING MUTATION F508DEL INHIBITS THE CONSTITUTIVE ACTIVITY FOR SLC26A9

被引：0

作者：

Bertrand, Carol A. ^{[1
]}

Mitra, Shalini ^{[1
]}

Mishra, Sanjay K. ^{[1
]}

Wang, Xiaohui ^{[1
]}

Zhao, Yu ^{[2
]}

Pilewski, Joseph M. ^{[3
]}

Madden, Dean R. ^{[2
]}

Frizzell, Raymond A. ^{[1
,4
]}

机构：

[1] Univ Pittsburgh, Sch Med, Pediat, Pittsburgh, PA USA

[2] Geisel Sch Med Dartmouth, Biochem & Cell Biol, Hanover, NH USA

[3] Unviers Pittsburgh, Sch Med, Pulm Allergy & Crit Care Med, Pittsburgh, PA USA

[4] Univ Pittsburgh, Sch Med, Cell Biol, Pittsburgh, PA USA

来源：

PEDIATRIC PULMONOLOGY | 2017年 / 52卷

基金：

美国国家卫生研究院;

关键词：

CYSTIC-FIBROSIS;

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

S09.4

引用

页码：S155 / S156

页数：2

共 6 条

[1] The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9 [J].

Bertrand, Carol A. ;

Mitra, Shalini ;

Mishra, Sanjay K. ;

Wang, Xiaohui ;

Zhao, Yu ;

Pilewski, Joseph M. ;

Madden, Dean R. ;

Frizzell, Raymond A. .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2017, 312 (06) :L912-L925

[2] SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia [J].

Bertrand, Carol A. ;

Zhang, Ruilin ;

Pilewski, Joseph M. ;

Frizzell, Raymond A. .

JOURNAL OF GENERAL PHYSIOLOGY, 2009, 133 (04) :421-438

[3] Genetic Modifiers of Cystic Fibrosis-Related Diabetes [J].

Blackman, Scott M. ;

Commander, Clayton W. ;

Watson, Christopher ;

Arcara, Kristin M. ;

Strug, Lisa J. ;

Stonebraker, Jaclyn R. ;

Wright, Fred A. ;

Rommens, Johanna M. ;

Sun, Lei ;

Pace, Rhonda G. ;

Norris, Sarah A. ;

Durie, Peter R. ;

Drumm, Mitchell L. ;

Knowles, Michael R. ;

Cutting, Garry R. .

DIABETES, 2013, 62 (10) :3627-3635

[4] Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis [J].

Miller, Melissa R. ;

Soave, David ;

Li, Weili ;

Gong, Jiafen ;

Pace, Rhonda G. ;

Boelle, Pierre-Yves ;

Cutting, Garry R. ;

Drumm, Mitchell L. ;

Knowles, Michael R. ;

Sun, Lei ;

Rommens, Johanna M. ;

Accurso, Frank ;

Durie, Peter R. ;

Corvol, Harriet ;

Levy, Hara ;

Sontag, Marci K. ;

Strug, Lisa J. .

JOURNAL OF PEDIATRICS, 2015, 166 (05) :1152-U603

[5] Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics [J].

Strug, Lisa J. ;

Gonska, Tanja ;

He, Gengming ;

Keenan, Katherine ;

Ip, Wan ;

Boelle, Pierre-Yves ;

Lin, Fan ;

Panjwani, Naim ;

Gong, Jiafen ;

Li, Weili ;

Soave, David ;

Xiao, Bowei ;

Tullis, Elizabeth ;

Rabin, Harvey ;

Parkins, Michael D. ;

Price, April ;

Zuberbuhler, Peter C. ;

Corvol, Harriet ;

Ratjen, Felix ;

Sun, Lei ;

Bear, Christine E. ;

Rommens, Johanna M. .

HUMAN MOLECULAR GENETICS, 2016, 25 (20) :4590-4600

[6] Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis [J].

Sun, Lei ;

Rommens, Johanna M. ;

Corvol, Harriet ;

Li, Weili ;

Li, Xin ;

Chiang, Theodore A. ;

Lin, Fan ;

Dorfman, Ruslan ;

Busson, Pierre-Francois ;

Parekh, Rashmi V. ;

Zelenika, Diana ;

Blackman, Scott M. ;

Corey, Mary ;

Doshi, Vishal K. ;

Henderson, Lindsay ;

Naughton, Kathleen M. ;

O'Neal, Wanda K. ;

Pace, Rhonda G. ;

Stonebraker, Jaclyn R. ;

Wood, Sally D. ;

Wright, Fred A. ;

Zielenski, Julian ;

Clement, Annick ;

Drumm, Mitchell L. ;

Boelle, Pierre-Yves ;

Cutting, Garry R. ;

Knowles, Michael R. ;

Durie, Peter R. ;

Strug, Lisa J. .

NATURE GENETICS, 2012, 44 (05) :562-+

← 1 →