Targeting the checkpoint kinase WEE1 Selective sensitization of cancer cells to DNA-damaging drugs

被引：21

作者：

Indovina, Paola ^{[1
,2
]}

Giordano, Antonio ^{[1
,2
,3
]}

机构：

[1] Univ Siena, Dept Human Pathol & Oncol, I-53100 Siena, Italy

[2] Temple Univ, Sbarro Inst Canc Res & Mol Med, Ctr Biotechnol, Coll Sci & Technol, Philadelphia, PA 19122 USA

[3] CROM, Avellino, Italy

来源：

CANCER BIOLOGY & THERAPY | 2010年 / 9卷 / 07期

关键词：

WEE1; G(2) checkpoint abrogators; DNA-damaging agents; p53-deficient cancer cells; MK-1775; G(2) CHECKPOINT; MICROSATELLITE INSTABILITY; TUMOR-CELLS; ABROGATION; CHK1; INHIBITOR; THERAPIES; P53;

D O I：

10.4161/cbt.9.7.11276

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：523 / 525

页数：3

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