MELATONIN BINDS MT1 TO IMPROVE THE PHENOTYPES OF PRIMARY SCLEROSING CHOLANGITIS (PSC) THROUGH CLOCK GENES/MIR-200B/MASPIN/GST SIGNALING

被引：0

作者：

Ceci, Ludovica ^{[1
]}

Carpino, Guido ^{[2
]}

Kennedy, Lindsey ^{[1
,3
]}

Wu, Nan ^{[1
]}

Chen, Lixian ^{[1
]}

Kyritsi, Konstantina ^{[1
]}

Zhou, Tianhao ^{[1
]}

Ekser, Burcin ^{[4
]}

Zhang, Wenjun ^{[4
]}

Onori, Paolo ^{[5
,6
]}

Franchitto, Antonio ^{[5
,6
]}

Mancinelli, Romina A. ^{[5
,6
]}

Wu, Chaodong ^{[7
]}

Gaudio, Eugenio ^{[5
,6
]}

Meadows, Vik ^{[1
]}

Francis, Heather L. ^{[1
,3
]}

Glaser, Shannon S. ^{[8
]}

Alpini, Gianfranco ^{[1
,3
]}

机构：

[1] Indiana Univ Sch Med, Dept Med, Div Gastroenterol & Hepatol, Indianapolis, IN 46202 USA

[2] Italian Univ Sport & Movement Foro Italico, Dept Hlth Sci, Rome, Italy

[3] Richard L Roudebush VA Med Ctr, Indianapolis, IN USA

[4] Indiana Univ Sch Med, Transplant Surg, Indianapolis, IN 46202 USA

[5] Sapienza Univ Rome, Internal Med & Med Specialties, Rome, Italy

[6] Sapienza Univ Rome, Dept Anat Histol Forens Med & Orthoped Sci, Rome, Italy

[7] Texas A&M Univ, Nutr & Food Sci, College Stn, TX 77843 USA

[8] Texas A&M Univ, Coll Med, Med Physiol, College Stn, TX 77843 USA

来源：

HEPATOLOGY | 2021年 / 74卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

432

引用

页码：273A / 274A

页数：2

共 4 条

[1] The melatonin/MT1/miR-200b axis regulates biliary senescence and liver fibrosis in the Mdr2-/- mouse model of primary sclerosing cholangitis
Wu, Nan
Meng, Fanyin
Invernizzi, Pietro
Venter, Julie
Bernuzzi, Francesca
Alvaro, Domenico
Onori, Paolo
Franchitto, Antonio
Zhou, Tianhao
Francis, Heather L.
Kyritsi, Tina
Mancinelli, Romina
Gaudio, Eugenio
Alpini, Gianfranco
Glaser, Shannon S.
HEPATOLOGY, 2016, 64 : 178A - 178A
[2] Melatonin Therapy Reduces Biliary Proliferation and Hepatic Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis (PSC) By Decreased Expression of miR-200b and Angiogenic Factors
Wu, Nan
Meng, Fanyin
Venter, Julie
Francis, Heather L.
Standeford, Holly
DeMorrow, Sharon
Franchitto, Antonio
Onori, Paolo
Gaudio, Eugenio
Alpini, Gianfranco
Glaser, Shannon
GASTROENTEROLOGY, 2016, 150 (04) : S1046 - S1046
[3] KNOCKDOWN OF THE MT1 MELATONIN RECEPTOR AMELIORATES THE PHENOTYPES OF THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC) BY DOWNREGULATION OF ORPHAN GPR50 RECEPTOR-PROMOTED CONSTITUTIVE TGF-β1 RECEPTOR SIGNALING
Wu, Nan
Ceci, Ludovica
Zhou, Tianhao
Francis, Heather L.
Kennedy, Lindsey
Kyritsi, Konstantina
Alvaro, Domenico
Carpino, Guido
Wu, Chaodong
Chakraborty, Sanjukta
Chen, Lixian
Baiocchi, Leonardo
Franchitto, Antonio
Ekser, Burcin
Onori, Paolo
Mancinelli, Romina
Grumbles, Kassidy
Gaudio, Eugenio
Glaser, Shannon S.
Alpini, Gianfranco
GASTROENTEROLOGY, 2021, 160 (06) : S768 - S768
[4] MELATONIN RECEPTOR 1A (MT1) KNOCKOUT DECREASES BILIARY DAMAGE AND LIVER STEATOSIS VIA DOWNREGULATION OF MIR-200B IN HIGH FAT DIET (HFD) MODEL OF NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)
Chen, Lixian
Kennedy, Lindsey
Ceci, Ludovica
Ekser, Burcin
Zhang, Wenjun
Zhou, Tianhao
Wu, Nan
Baiocchi, Leonardo
Kyritsi, Konstantina
Meadows, Vik
Kundu, Debjyoti
Meyer, Alison A.
Francis, Heather L.
Alpini, Gianfranco
Glaser, Shannon S.
GASTROENTEROLOGY, 2022, 162 (07) : S1266 - S1266

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