Fusion of contrast-enhanced breast MR and mammographic imaging data

被引:38
作者
Behrenbruch, CP
Marias, K
Armitage, PA
Yam, M
Moore, N
English, RE
Clarke, J
Brady, M
机构
[1] Univ Oxford, Dept Engn Sci, Med Vis Lab Robot, Oxford OX1 3PJ, England
[2] UCL, Royal Free & Univ Coll Med Sch, Dept Surg, London NW3 2QG, England
[3] John Radcliffe Hosp, Magnet Resonance Imaging Ctr, Oxford OX3 9DU, England
[4] Churchill Hosp, Breast Care Unit, Oxford OX3 7LJ, England
[5] Churchill Hosp, Dept Surg, Oxford OX3 7LJ, England
关键词
D O I
10.1016/S1361-8415(03)00015-X
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
increasing use is being made of Gd-DTPA contrast-enhanced magnetic resonance imaging for breast cancer assessment since it provides 3D functional information via pharmacokinetic interaction between contrast agent and tumour vascularity, and because it is applicable to women of all ages as well as patients with post-operative scarring. Contrast-enhanced MRI (CE-MRI) is complementary to conventional X-ray mammography, since it is a relatively low-resolution functional counterpart of a comparatively high-resolution 2D structural representation. However, despite the additional information provided by MRI, mammography is still an extremely important diagnostic imaging modality, particularly for several common conditions such as ductal carcinoma in situ (DCIS) where it has been shown that there is a strong correlation between microcalcification clusters and malignancy. Pathological indicators such as calcifications and fine spiculations are not visible in CE-MRI and therefore there is clinical and diagnostic value in fusing the high-resolution structural information available from mammography with the functional data acquired from MRI imaging. This paper presents a novel data fusion technique whereby medial-lateral oblique (MLO) and cranial-caudal (CC) mammograms (2D data) are registered to 3D contrast-enhanced MRI volumes. We utilise a combination of pharmacokinetic modelling, projection geometry, wavelet-based landmark detection and thin-plate spline non-rigid 'warping' to transform the coordinates of regions of interest (ROIs) from the 2D mammograms to the spatial reference frame of the contrast-enhanced MRI volume. Of key importance is the use of a flexible wavelet-based feature extraction technique that enables feature correspondences to be robustly determined between the very different image characteristics of X-ray mammography and MRI. An evaluation of the fusion framework is demonstrated with a series of clinical cases and a total of 14 patient examples. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:311 / 340
页数:30
相关论文
共 50 条
[31]   Detection of breast cancer with conventional mammography and contrast-enhanced MR imaging [J].
Kacl, GM ;
Liu, PF ;
Debatin, JF ;
Garzoli, E ;
Caduff, RE ;
Krestin, GP .
EUROPEAN RADIOLOGY, 1998, 8 (02) :194-200
[32]   A multipurpose phantom for quality assurance of contrast-enhanced MR imaging of the breast [J].
Fischer, U ;
Döler, W ;
Luftner-Nagel, S ;
Grabbe, E .
EUROPEAN RADIOLOGY, 2000, 10 (01) :162-166
[33]   Anatomical landmark localization in breast dynamic contrast-enhanced MR imaging [J].
X. X. Yin ;
B. W.-H. Ng ;
Q. Yang ;
A. Pitman ;
K. Ramamohanarao ;
D. Abbott .
Medical & Biological Engineering & Computing, 2012, 50 :91-101
[34]   Anatomical landmark localization in breast dynamic contrast-enhanced MR imaging [J].
Yin, X. X. ;
Ng, B. W. -H. ;
Yang, Q. ;
Pitman, A. ;
Ramamohanarao, K. ;
Abbott, D. .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2012, 50 (01) :91-101
[35]   Breast contrast-enhanced MR imaging: semiautomatic detection of vascular map [J].
Fusco, Roberta ;
Sansone, Mario ;
Filice, Salvatore ;
Petrillo, Antonella .
BREAST CANCER, 2016, 23 (02) :266-272
[36]   Dynamic contrast-enhanced breast MR imaging in men: Preliminary results [J].
Morakkabati-Spitz, N ;
Schild, HH ;
Leutner, CC ;
von Falkenhausen, M ;
Lutterbey, G ;
Kuhl, CK .
RADIOLOGY, 2006, 238 (02) :438-445
[37]   Myocardial perfusion by contrast-enhanced echocardiography and dynamic contrast-enhanced MR imaging [J].
Lombardi, M ;
Rovai, D ;
Rinck, PA ;
LAbbate, A .
ACTA RADIOLOGICA, 1997, 38 :79-84
[38]   MR elastography as an adjunct to contrast-enhanced breast MR imaging: First clinical results [J].
Kuhl, CK ;
Sonderman, E ;
Leutner, CC ;
Simon, B ;
Sinkus, R ;
Schild, HH .
RADIOLOGY, 2002, 225 :324-324
[39]   Enhanced Mass on Contrast-Enhanced Breast MR Imaging: Lesion Characterization Using Combination of Dynamic Contrast-Enhanced and Diffusion-Weighted MR Images [J].
Yabuuchi, Hidetake ;
Matsuo, Yoshio ;
Okafuji, Takashi ;
Kamitani, Takeshi ;
Soeda, Hiroyasu ;
Setoguchi, Taro ;
Sakai, Shuji ;
Hatakenaka, Masamitsu ;
Kubo, Makoto ;
Sadanaga, Noriaki ;
Yamamoto, Hidetaka ;
Honda, Hiroshi .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2008, 28 (05) :1157-1165
[40]   Spiral imaging for dynamic contrast-enhanced MR imaging [J].
Poonawalla, AH ;
Stafford, RJ ;
Glover, GH ;
Hazle, JD .
RADIOLOGY, 1999, 213P :196-196