Hepatitis B: Prevalence and occult infection in HIV-infected patients

被引：6

作者：

Calux, Samira Julien ^{[1
]}

Martins Silva, Vanessa Cristina ^{[1
]}

Compri, Adriana Parise ^{[1
]}

Lemos, Marcilio Figueiredo ^{[1
]}

de Torres Santos, Ana Paula ^{[2
]}

Oba, Isabel Takano ^{[1
]}

Mendes-Correa, Maria Cassia J. ^{[3
]}

Moreira, Regina Celia ^{[1
]}

机构：

[1] Adolfo Lutz Inst, Lab Hepatites Virais, Ctr Virol, Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Div Lab Cent, Hosp Clin, Sao Paulo, SP, Brazil

[3] Univ Sao Paulo, Dept Doencas Infecciosas, Sao Paulo, SP, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2020年 / 53卷

关键词：

Prevalence; Occult hepatitis B infection; HBV; HIV; HUMAN-IMMUNODEFICIENCY-VIRUS;

D O I：

10.1590/0037-8682-0533-2018

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. Methods: All samples were tested for serology markers and using qPCR. Results: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. Conclusions: We observed a high prevalence of HBV among HIV patients. In addition the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.

引用

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