Crystal structure of ethyl 2-(5-amino-1-benzene-sulfonyl-3-oxo-2,3-dihydro-1H-pyrazol-2-yl)acetate

被引：6

作者：

Metwally, Nadia H. ^{[1
]}

Elgemeie, Galal H. ^{[2
]}

Jones, Peter G. ^{[3
]}

机构：

[1] Cairo Univ, Fac Sci, Chem Dept, Giza, Egypt

[2] Helwan Univ, Fac Sci, Chem Dept, Cairo, Egypt

[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Anorgan & Analyt Chem, Hagenring 30, D-38106 Braunschweig, Germany

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2020年 / 76卷

关键词：

crystal structure; pyrazine; sulfonyl; hydrogen bonds; ANTIMICROBIAL EVALUATION;

D O I：

10.1107/S2056989020002674

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C13H15N3O5S, the two rings face each other in a 'V' form at the S atom, with one N-H center dot center dot center dot O=S and one C-H center dot center dot center dot O=S contact from the pyrazolyl substituents to the sulfonyl group. Two classical hydrogen bonds from the amine group, one of the form N-H center dot center dot center dot O=S and one N-H center dot center dot center dot O Coxo, link the molecules to form layers parallel to the bc plane.

引用

收藏

页码：481 / +

页数：8

相关论文

共 19 条

[1]

Azzam R. A., 2019, J MOL STRUCT, V1173, P707

[2] Crystal structure of potassium [4-amino-5-(benzo-[d]thiazol-2-yl)-6-(methylsulfanyl)pyrimidin-2-yl]-(phenylsulfonyl)azanide dimethylformamide monosolvate hemihydrate [J].

Azzam, Rasha A. ;

Elgemeie, Galal H. ;

Osman, Rokia R. ;

Jones, Peter G. .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2019, 75 :367-+

[3] Synthesis and antimicrobial evaluation of novel N-substituted 4-ethylsulfanyl-2-pyridones and triazolopyridines [J].

Azzam, Rasha A. ;

Elgemeie, Galal H. .

MEDICINAL CHEMISTRY RESEARCH, 2019, 28 (01) :62-70

[4]

Azzam RA, 2017, ACTA CRYSTALLOGR E, V73, P1820, DOI 10.1107/S2056989017015778

[5] Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino-and 5-benzoyl-N-sulfonylamino-4alkylsulfanyl-2-pyridones [J].

Elgemeie, Galal ;

Altalbawy, Farag ;

Alfaidi, Mohammed ;

Azab, Rania ;

Hassan, Atef .

DRUG DESIGN DEVELOPMENT AND THERAPY, 2017, 11 :3389-3399

[6] Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000-2018) [J].

Elgemeie, Galal H. ;

Azzam, Rasha A. ;

Elsayed, Rasha E. .

MEDICINAL CHEMISTRY RESEARCH, 2019, 28 (08) :1099-1131

[7] True symmetry or pseudosymmetry: 5-amino-1-(4-methylphenylsulfonyl)-4-pyrazolin-3-one and a comparison with its 1-phenylsulfonyl analogue [J].

Elgemeie, Galal H. ;

Sayed, Shahinaz H. ;

Jones, Peter G. .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2013, 69 :90-+

[8] 5-amino-1-phenylsulfonyl-4-pyrazolin-3-one [J].

Elgemeie, GEH ;

Hanfy, N ;

Hopf, H ;

Jones, PG .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1998, 54 :136-138

[9] Novel synthesis of 5-amino-1-arylsulfonyl-4-pyrazolin-3-ones as a new class of N-sulfonylated pyrazoles [J].

Elgemeie, GH ;

Metwally, NH .

JOURNAL OF CHEMICAL RESEARCH, 1999, (06) :384-385

[10] N-[3-Cyano-2-oxo-5,6,7,8-tetrahydroquinoline-1(2H)-yl]-4-methylbenzenesulfonamide [J].

Elgemeie, GH ;

Jones, PG .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2002, 58 :O1250-O1252