Characterization of clinical and food Listeria monocytogenes isolates with different antibiotic resistance patterns through simulated gastrointestinal tract conditions and environmental stresses

被引：15

作者：

Cunha, S. ^{[1
]}

Komora, N. ^{[1
]}

Magalhaes, R. ^{[1
]}

Almeida, G. ^{[1
]}

Ferreira, V. ^{[1
]}

Teixeira, P. ^{[1
]}

机构：

[1] Univ Catolica Portuguesa Porto, Escola Super Biotecnol, Lab Associado, CBQF, Rua Arquiteto Lobao Vital,Apartado 2511, P-2511401 Porto, Portugal

来源：

MICROBIAL RISK ANALYSIS | 2016年 / 1卷

关键词：

Listeria monocytogenes; Acid stress; Alkali stress; Gastro-intestinal tract; Antibiotic resistance;

D O I：

10.1016/j.mran.2015.08.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Thirty-three Listeria monocyfogenes isolates previously collected from two sources, food (n = 18) and human patients suffering from listeriosis (n = 15), with variable antibiotic susceptibility profiles (sensitive/resistant) to erythromycin, ciprofloxacin and nitrofurantoin, were studied for their ability to survive (i) the environmental stress provided by sequential conditions that simulate the digestive tract, and (ii) extreme pH values (1.5-12). The results showed a response that was only strain dependent. There were no variability in survival results based on type of stress (low or high pH), source (food or clinical), or sensitivity/resistance to antibiotics (p > 0.01). Some strains of L. monocytogenes are able to survive extreme acid and alkaline conditions, and conditions that mimic the sequential stressors found in the gastro-intestinal tract. The resistance to the antibiotics tested in this study by some L. monocytogenes strains did not confer any cross-protection to acid or alkaline stressors. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：40 / 46

页数：7

共 45 条

[1] Susceptibility of Listeria monocytogenes strains to disinfectants and chlorinated alkaline cleaners at cold temperatures [J].