Comparative Analysis of Metabolic Differences of Jersey Cattle in Different High-Altitude Areas

被引：8

作者：

Kong, Zhiwei ^{[1
,2
,3
]}

Li, Bin ^{[4
]}

Zhou, Chuanshe ^{[5
]}

He, Qinghua ^{[1
]}

Zheng, Yuzhong ^{[3
]}

Tan, Zhiliang ^{[5
]}

机构：

[1] Shenzhen Univ, Coll Chem & Environm Engn, Dept Food Sci & Engn, Shenzhen, Peoples R China

[2] Shenzhen Univ, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Coll Optoelect Engn, Shenzhen, Peoples R China

[3] Hanshan Nornal Univ, Sch Food Engn & Biotechnol, Chaozhou, Peoples R China

[4] Tibet Autonomous Reg Acad Agr Sci, Inst Anim Husb & Vet, State Key Lab Hulless Barley & Yak Germplasm Reso, Lhasa, Peoples R China

[5] Chinese Acad Sci, Inst Subtrop Agr, CAS Key Lab Agroecol Proc Subtrop Reg,Natl Engn L, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Changsha, Peoples R China

来源：

FRONTIERS IN VETERINARY SCIENCE | 2021年 / 8卷

基金：

中国国家自然科学基金;

关键词：

metabonomics; high altitude; Jersey cattle; difference; hypoxia; NITRIC-OXIDE; HYPOXIA; CELLS; REVEALS; ADAPTATION; EXPRESSION; THERAPY; ENOS;

D O I：

10.3389/fvets.2021.713913

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In high-altitude area, hypoxia is a serious stress for humans and other animals, disrupting oxygen homeostasis and thus affecting tissue metabolism. Up to now, there are few reports on the metabolic changes of dairy cows at different altitudes. In this experiment, metabonomics technology and blood biochemical indexes were used to study the metabolic changes of dairy cows in different altitudes. The results showed that the different metabolites were mainly enriched in amino acid metabolism and sphingolipid metabolism, and sphingolipid metabolism showed a negative correlation with increased altitude. The results of this study will enrich the hypoxia-adaptive mechanism of dairy cows in high-altitude areas and provide a theoretical basis for the nutritional regulation of performance and disease treatment of dairy cows in high-altitude areas.

引用

页数：8

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