Birefringence measurement of the retinal nerve fiber layer by swept source polarization sensitive optical coherence tomography

被引：21

作者：

Elmaanaoui, Badr ^{[1
]}

Wang, Bingqing ^{[2
]}

Dwelle, Jordan C. ^{[2
]}

McElroy, Austin B. ^{[2
]}

Liu, Shuang S. ^{[2
]}

Rylander, Henry G., III ^{[2
]}

Milner, Thomas E. ^{[2
]}

机构：

[1] Univ Texas Austin, Dept Elect & Comp Engn, Austin, TX 78712 USA

[2] Univ Texas Austin, Dept Biomed Engn, Austin, TX 78712 USA

来源：

OPTICS EXPRESS | 2011年 / 19卷 / 11期

关键词：

SPECTRAL-DOMAIN OCT; HIGH-SPEED; BIOLOGICAL TISSUE; AXIS ORIENTATION; THICKNESS; VISUALIZATION; REFLECTOMETER;

D O I：

10.1364/OE.19.010252

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A Swept Source Polarization-Sensitive Optical Coherence Tomography (SS-PS-OCT) instrument has been designed, constructed, and verified to provide high sensitivity depth-resolved birefringence and phase retardation measurements of the retinal nerve fiber layer. The swept-source laser had a center wavelength of 1059 nm, a full-width-half-max spectral bandwidth of 58 nm and an A-line scan rate of 34 KHz. Power incident on the cornea was 440 mu W and measured axial resolution was 17 mu m in air. A multiple polarization state nonlinear fitting algorithm was used to measure retinal birefringence with low uncertainty. Maps of RNFL phase retardation in a subject measured with SS-PS-OCT compare well with those generated using a commercial scanning laser polarimetry instrument. Peak-to-valley variation of RNFL birefringence given here is less than values previously reported at 840nm. (C)2011 Optical Society of America

引用

页码：10252 / 10268

页数：17

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