Direct Leuckart-type reductive amination of aldehydes and ketones: a facile one-pot protocol for the preparation of secondary and tertiary amines

被引：34
|
作者：
O'Connor, Danielle [1 ]
Lauria, Ashley [1 ]
Bondi, Steven P. [1 ]
Saba, Shahrokh [1 ]
机构：
[1] Fordham Univ, Dept Chem, Bronx, NY 10458 USA
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 01期
基金：
美国国家科学基金会;
关键词：
Reductive amination; Secondary amines; Tertiary amines; Aldehydes; Ketones; METHYLPIPERIDINE ZINC BOROHYDRIDE; SELECTIVE REDUCING AGENT; CHLORIDE HYDRIDE COMPLEX; CARBONYL-COMPOUNDS; SODIUM CYANOBOROHYDRIDE; ORGANIC-SYNTHESIS; BORANE-PYRIDINE; N-ALKYLATION; SILICA-GEL; IMINES;
D O I：
10.1016/j.tetlet.2010.11.006
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A high-yielding and facile one-pot Leuckart-type reaction for rapid access to a number of 2 degrees and 3 degrees amines is described. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：129 / 132
页数：4
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