Direct Leuckart-type reductive amination of aldehydes and ketones: a facile one-pot protocol for the preparation of secondary and tertiary amines

被引：34
|
作者：
O'Connor, Danielle [1 ]
Lauria, Ashley [1 ]
Bondi, Steven P. [1 ]
Saba, Shahrokh [1 ]
机构：
[1] Fordham Univ, Dept Chem, Bronx, NY 10458 USA
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 01期
基金：
美国国家科学基金会;
关键词：
Reductive amination; Secondary amines; Tertiary amines; Aldehydes; Ketones; METHYLPIPERIDINE ZINC BOROHYDRIDE; SELECTIVE REDUCING AGENT; CHLORIDE HYDRIDE COMPLEX; CARBONYL-COMPOUNDS; SODIUM CYANOBOROHYDRIDE; ORGANIC-SYNTHESIS; BORANE-PYRIDINE; N-ALKYLATION; SILICA-GEL; IMINES;
D O I：
10.1016/j.tetlet.2010.11.006
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A high-yielding and facile one-pot Leuckart-type reaction for rapid access to a number of 2 degrees and 3 degrees amines is described. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：129 / 132
页数：4
相关论文
共 50 条
  • [31] Stable Preformed Chiral Palladium Catalysts for the One-Pot Asymmetric Reductive Amination of Ketones
    Rubio-Perez, Laura
    Perez-Flores, F. Javier
    Sharma, Pankaj
    Velasco, Luis
    Cabrera, Armando
    ORGANIC LETTERS, 2009, 11 (02) : 265 - 268
  • [32] Highly chemoselective reductive amination by one pot reaction of aldehydes, amines and Dihydropyridine Catalyzed by TMSCl
    N. Azizi
    A. R. Khajeh Amiri
    H. Ghafuri
    M. R. Saidi
    M. Bolourtchian
    Journal of the Iranian Chemical Society, 2010, 7 : 428 - 431
  • [33] One-Pot direct reductive amination of furfural over Pd@CNTs
    Singh, Gurmeet
    Kaishyop, Jyotishman
    Singh, Gaje
    Gazi, Md. Jahiruddin
    Bag, Arijit
    Samanta, Chanchal
    Bordoloi, Ankur
    MOLECULAR CATALYSIS, 2023, 535
  • [34] Mild and efficient synthesis of secondary aromatic amines by one-pot stepwise reductive amination of arylaldehydes with nitroarenes promoted by reusable nickel nanoparticles
    Fiore, Ambra Maria
    Romanazzi, Giuseppe
    Dell'Anna, Maria Michela
    Latronico, Mario
    Leonelli, Cristina
    Mali, Matilda
    Rizzuti, Antonino
    Mastrorilli, Piero
    MOLECULAR CATALYSIS, 2019, 476
  • [35] Flow synthesis of secondary amines over Ag/Al2O3 catalyst by one-pot reductive amination of aldehydes with nitroarenes
    Artiukha, Ekaterina A.
    Nuzhdin, Alexey L.
    Bukhtiyarova, Galina A.
    Bukhtiyarov, Valerii I.
    RSC ADVANCES, 2017, 7 (72): : 45856 - 45861
  • [36] First example of direct reductive amination of aldehydes with primary and secondary amines catalyzed by water-soluble transition metal catalysts
    Robichaud, Andre
    Ajjou, Abdelaziz Nait
    TETRAHEDRON LETTERS, 2006, 47 (22) : 3633 - 3636
  • [37] One-Pot Synthesis of Symmetrical Tertiary and Secondary Amines from Carbonyl Compounds, Ammonium Carbonate and Carbon Monoxide as a Reductant
    Muratov, Karim
    Afanasyev, Oleg, I
    Kuchuk, Ekaterina
    Runikhina, Sofiya
    Chusov, Denis
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 2019 (38) : 6557 - 6560
  • [38] Metal-free, an effective and one-pot protocol for the reductive amination of aldehydes using glycerol as a green solvent
    Shripad M Patil
    Ashwini V Bedre
    Vilas B Gade
    Manohar K Jopale
    Journal of Chemical Sciences, 135
  • [39] One-pot preparation of ternary and quaternary iminium salts from aldehydes and ketones
    Saba, Shahrokh
    Vrkic, Diane
    Cascella, Clair
    DaSilva, Ida
    Carta, Kristine
    Kojtari, Adeline
    JOURNAL OF CHEMICAL RESEARCH, 2008, (06) : 301 - 304
  • [40] One-pot, three-component synthesis of secondary amines and trisubstituted hydrazines from ketones
    Tavakol, H.
    Zakery, S.
    CHEMICAL PAPERS, 2006, 60 (04): : 315 - 317
12345