Continuous transversus abdominis plane block catheter analgesia for postoperative pain control in renal transplant

被引:33
作者
Farag, Ehab [1 ,2 ]
Guirguis, Maged N. [3 ]
Helou, Mada [4 ]
Dalton, Jarrod E. [2 ,5 ]
Ngo, Fallon [4 ]
Ghobrial, Michael [4 ]
O'Hara, Jerome [1 ]
Seif, John [6 ]
Krishnamurthi, Venkatesh [7 ]
Goldfarb, David [7 ]
机构
[1] Cleveland Clin, Dept Gen Anesthesiol, Cleveland, OH 44195 USA
[2] Cleveland Clin, Dept Outcomes Res, Cleveland, OH 44195 USA
[3] Cleveland Clin, Dept Pain Management, Cleveland, OH 44195 USA
[4] Cleveland Clin, Inst Anesthesiol, Cleveland, OH 44195 USA
[5] Cleveland Clin, Dept Quantitat Hlth Sci, Cleveland, OH 44195 USA
[6] Cleveland Clin, Dept Pediat Anesthesiol, Cleveland, OH 44195 USA
[7] Cleveland Clin, Dept Urol, Cleveland, OH 44195 USA
关键词
Local anesthetic - ropivacaine; Opioid analgesics - morphine; Abdominal surgery; Kidney transplantation; TAP catheter; Nausea; RANDOMIZED CONTROLLED-TRIAL; TAP BLOCK; RECIPIENTS;
D O I
10.1007/s00540-014-1855-1
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Purpose Continuous transversus abdominis plane (TAP) block using a catheter has proven its usefulness in reducing opioid requirements and pain scores after lower abdominal surgery. However, there are no reports of its successful use after renal transplant. We tested the hypothesis that continuous TAP block would retrospectively reduce opioid requirement, nausea score and hospital stay after renal transplant surgery. Methods In a retrospective study, we reviewed the data from 63 adult renal transplant recipients-31 with patient-controlled TAP analgesia with standing orders for intravenous as well as oral opioids as needed and 32 with intravenous patient-controlled analgesia. The TAP catheter was inserted preoperatively using an ultrasound-guided technique. Infusion of ropivacaine 0.2 % at 8 ml basal, 12 ml bolus and a lockout interval of 60 min were maintained for 48 h postoperatively. The primary outcome was total morphine-equivalent dose during the 48-h postoperative period. Secondary outcomes were pain and nausea scores for the 48-h postoperative period. Results The mean 48-h postoperative morphine-equivalent doses [95 % confidence interval] for patient-controlled intravenous analgesia and TAP catheter were 197 [111, 349] and 50 [28, 90], respectively, which were significantly different (P = 0.002). The mean 48-h average verbal response pain scores were 2.94 [2.39, 3.50] and 2.49 [1.93, 3.06], respectively, which were not significantly different (P = 0.26). The mean nausea scores were 0.66 [0.46, 0.87] and 0.60 [0.40, 0.81], respectively, which were not significantly different (P = 0.69). There was no difference regarding hospital stay. Conclusion The use of continuous TAP analgesia for postoperative analgesia after renal transplant was effective in reducing the morphine-equivalent requirements.
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页码:4 / 8
页数:5
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