Salvia divinorum: toxicological aspects and analysis in human biological specimens

被引：5
作者：
Margalho, Claudia [1 ]
Corte-Real, Francisco [1 ,2 ]
Lopez-Rivadulla, Manuel [3 ]
Gallardo, Eugenia [4 ,5 ]
机构：
[1] IP, INMLCF, Delegacao Ctr, Coimbra, Portugal
[2] Univ Coimbra, Fac Med, P-3000 Coimbra, Portugal
[3] Univ Santiago de Compostela, Inst Univ Ciencias Forenses, Serv Toxicol Forense, Santiago De Compostela, Spain
[4] Univ Beira Interior, Ctr Invest Ciencias Saude CICS UBI, Covilha, Portugal
[5] Univ Beira Interior, Lab Farmacotoxicol UBIMed, Covilha, Portugal
来源：
BIOANALYSIS | 2016年 / 8卷 / 13期
关键词：
analytical methodologies; Salvia divinorum; salvinorin A; PLANT-DERIVED HALLUCINOGEN; SALVINORIN-A; NEOCLERODANE DITERPENOIDS; LIQUID-CHROMATOGRAPHY; VITREOUS-HUMOR; DRUGS; MINT; SAGE; COMPONENT; FLUIDS;
D O I：
10.4155/bio-2016-0067
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The identification and quantitation of the main psychoactive component of Salvia divinorum (salvinorin A) in biological specimens are crucial in forensic and clinical toxicology. Despite all the efforts made, its uncontrolled abuse has increased quickly, exposing its users' health to serious risks both in the short and long term. The use of alternative biological matrices in toxicological analyzes can be advantageous as complementary postmortem samples, or in situations when neither blood nor urine can be collected; they may be useful tools in those determinations, providing important information about prior exposure. The aim of this article is to present a brief summary of legal aspects of Salvia divinorum and salvinorin A, including the methods used for the determination of the latter in biological matrices.
引用
收藏
页码：1415 / 1425
页数：11
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