A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering

被引:105
作者
Zhang, Xu [1 ]
Tan, Bowen [1 ]
Wu, Yanting [1 ]
Zhang, Min [1 ]
Liao, Jinfeng [1 ]
机构
[1] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, State Key Lab Oral Dis, Chengdu 610041, Peoples R China
关键词
hydrogel; photothermal effect; antibacterial; angiogenesis; wound healing; bone regeneration; SUPRAMOLECULAR HYDROGEL; DRUG-RELEASE; DEGRADABLE HYDROGEL; THERAPY; ADHESIVE; ANTIBACTERIAL; NANOPARTICLES; REGENERATION; TUMOR; STRATEGY;
D O I
10.3390/polym13132100
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Photothermal treatment (PTT) is a promising strategy to deal with multidrug-resistant bacteria infection and promote tissue regeneration. Previous studies demonstrated that hyperthermia can effectively inhibit the growth of bacteria, whereas mild heat can promote cell proliferation, further accelerating wound healing and bone regeneration. Especially, hydrogels with photothermal properties could achieve remotely controlled drug release. In this review, we introduce a photothermal agent hybrid in hydrogels for a photothermal effect. We also summarize the potential mechanisms of photothermal hydrogels regarding antibacterial action, angiogenesis, and osteogenesis. Furthermore, recent developments in photothermal hydrogels in wound healing and bone regeneration applications are introduced. Finally, future application of photothermal hydrogels is discussed. Hydrogels with photothermal effects provide a new direction for wound healing and bone regeneration, and this review will give a reference for the tissue engineering.
引用
收藏
页数:21
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