RETRACTED: Serum Levels of 25-Hydroxyvitamin D and Functional Outcome among Postmenopausal Women with Hip Fracture (Retracted Article)

被引:4
作者
Liu, Lan-Mei [1 ]
Wang, Shuai-Hua [1 ]
Fu, Chuan-Sheng [1 ]
Han, Xiang-Zhen [1 ]
Wei, Bao-Fu [2 ]
机构
[1] Linyi Peoples Hosp, Dept Orthoped, Linyi, Shandong, Peoples R China
[2] Shandong Prov Hosp, Hand & Foot Surg Dept, Jinan, Shandong, Peoples R China
来源
PLOS ONE | 2015年 / 10卷 / 01期
关键词
VITAMIN-D STATUS; BONE TURNOVER; D DEFICIENCY; OLDER WOMEN; OSTEOPOROSIS; ASSOCIATION; PREVALENCE; RECOVERY; MARKERS; RISK;
D O I
10.1371/journal.pone.0116375
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective The main objective of the current study was to assess the distribution and its prognostic value of serum 25-hydroxyvitamin D (25[OH] D) levels assessed at admission in Chinese postmenopausal women with hip fracture. Methods From January 1, 2012 to December 31, 2013, all postmenopausal women with first-ever hip fracture were recruited to participate in the study. Serum 25[OH] D levels were measured at admission. The functional evaluation at the time of discharge was performed by the Barthel Index (BI). The prognostic value of 25[OH] D to predict the functional outcome within discharge was analyzed by logistic regression analysis, after adjusting for the possible confounders. Results In our study, 261 patients were included and assessed. In the 76 patients with an unfavorable functional outcome, serum 25(OH) D levels were lower compared with those in patients with a favorable outcome [11.8(IQR, 9.9-16.1) ng/ml; 16.8(IQR, 13.6-21.4) ng/ml, respectively; P<0.0001]. In multivariate analysis, there was an increased risk of unfavorable outcome associated with serum 25(OH) D levels <= 20ng/ml (OR 5.24, 95% CI: 3.11-8.15; P<0.0001) after adjusting for possible confounders. Conclusions Our data support an association between serum 25[OH] D levels and prognosis in Chinese postmenopausal women with hip fracture.
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页数:9
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