Effect of Varicocelectomy on Testicular Volume in Children and Adolescents: A Meta-analysis
被引:42
作者:
Li, Fuping
论文数: 0引用数: 0
h-index: 0
机构:Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Li, Fuping
论文数: 引用数:
h-index:
机构:
Chiba, Koji
Yamaguchi, Kohei
论文数: 0引用数: 0
h-index: 0
机构:
Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, JapanKobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Yamaguchi, Kohei
[1
]
论文数: 引用数:
h-index:
机构:
Okada, Keisuke
Matsushita, Kei
论文数: 0引用数: 0
h-index: 0
机构:Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Matsushita, Kei
Ando, Makoto
论文数: 0引用数: 0
h-index: 0
机构:Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Ando, Makoto
Yue, Huanxun
论文数: 0引用数: 0
h-index: 0
机构:Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Yue, Huanxun
Fujisawa, Masato
论文数: 0引用数: 0
h-index: 0
机构:Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
Fujisawa, Masato
机构:
[1] Kobe Univ, Grad Sch Med, Dept Surg Related, Div Urol,Fac Med,Chuo Ku, Kobe, Hyogo 6500017, Japan
OBJECTIVE To evaluate the effect of surgical intervention on catch-up growth as determined by a decreased testicular volume discrepancy in children and adolescents with varicocele. METHODS A systematic search was performed using MEDLINE and the PubMed database and cross-referenced as of October 28, 2011 using the terms "varicocele," "children," "adolescent," "surgery," and "testicular volume." All relevant studies were of the testicular volume discrepancy variance before and after surgical repair. The outcomes included the number of patients with initial testicular atrophy and those with catch-up growth after surgical repair. The database search, quality evaluation, and data extraction were independently performed by 2 reviewers. RESULTS Of 75 studies, 14 were included for analysis and involved 1475 patients. The combined analysis showed that the testicular volume discrepancy was significantly reduced after surgery in the >= 10% group (P < .00001) and >= 20% group (P < .00001), respectively. No difference was found between the 2 groups (P = .70). Taken together, the number of patient with testicular volume disproportion in all pediatric and adolescent varicocele patients significantly decreased after surgery (P < .00001). The average proportion of catch-up growth was 76.4% (range 52.6%-93.8%). CONCLUSION The meta-analysis suggested clear advantages of surgical intervention on reducing testicular hypotrophy when the discrepancy is >= 10% in children and adolescents with varicocele. Additional prospective and controlled studies are warranted to elucidate the treatment of children and adolescents with varicocele. UROLOGY 79: 1340-1345, 2012. (C) 2012 Elsevier Inc.
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
DeCastro, G. Joel
Shabsigh, Ahmad
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Shabsigh, Ahmad
Poon, Stephen A.
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Poon, Stephen A.
Laor, Laurent
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Laor, Laurent
Glassberg, Kenneth I.
论文数: 0引用数: 0
h-index: 0
机构:
Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USAMorgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
DeCastro, G. Joel
Shabsigh, Ahmad
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Shabsigh, Ahmad
Poon, Stephen A.
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Poon, Stephen A.
Laor, Laurent
论文数: 0引用数: 0
h-index: 0
机构:Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA
Laor, Laurent
Glassberg, Kenneth I.
论文数: 0引用数: 0
h-index: 0
机构:
Morgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USAMorgan Stanley Childrens Hosp New York Presbyteri, Div Pediat Urol, New York, NY 10032 USA