Copper-Catalyzed Aerobic Aliphatic C-H Oxygenation Directed by an Amidine Moiety

被引：187

作者：

Wang, Yi-Feng ^{[1
]}

Chen, Hui ^{[1
]}

Zhu, Xu ^{[1
]}

Chiba, Shunsuke ^{[1
]}

机构：

[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 29期

关键词：

OXIDATION REACTIONS; BONDS; FUNCTIONALIZATIONS; HYDROXYLATION; DERIVATIVES; REAGENTS; INSIGHTS; OXIDANT; COMPLEX; OLEFINS;

D O I：

10.1021/ja305833a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the oxygenation of tertiary C-H bonds of N-alkylamidines and N-(2-alkylaryl)-amidines is described that utilizes the CuBr center dot SMe2/2,2'-bipyridine catalytic system under an O-2 atmosphere and provides dihydrooxazoles, and 4H-1,3-benzoxazines. The oxygen atom is incorporated from atmospheric molecular oxygen during the present process.

引用

页码：11980 / 11983

页数：4

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