Synthesis of an anion-binding amino acid

被引：1

作者：

Chenard, Sylvain

Barberis, Claude

Otis, Francois

Paquin, Jean-Francois

Martel, Jonathan

Banville, Charles

Voyer, Normand ^{[1
]}

机构：

[1] Univ Laval, Dept Chim, Quebec City, PQ G1V 0A6, Canada

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 04期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Unnatural amino acid; Diazamacrocycle; Macrocyclization; Anion binding; PEPTIDE-SYNTHESIS; DESIGN; NANOSTRUCTURES; COMPLEXES; ESTERS;

D O I：

10.1016/j.tetlet.2011.11.057

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We achieved the synthesis of a derivative of phenylalanine with a diazamacrocycle on its side chain by macrocyclization of a dichloride on L-DOPA. We also report its incorporation into peptide structures by solid phase peptide synthesis which will lead to the development of artificial anion channels. (C) 2011 Elsevier Ltd. All rights reserved.

引用

收藏

页码：409 / 411

页数：3

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