Synthesis and NMR study of two lipophilic iron(III) sequestering agents based on 8-hydroxyquinoline; H-bonding and conformational changes

被引：50

作者：

Caris, C ^{[1
]}

Baret, P ^{[1
]}

Pierre, JL ^{[1
]}

Serratrice, G ^{[1
]}

机构：

[1] UNIV GRENOBLE 1,LEDSS,LAB CHIM BIOMIMET,URA CNRS 332,F-38041 GRENOBLE 9,FRANCE

来源：

TETRAHEDRON | 1996年 / 52卷 / 13期

关键词：

D O I：

10.1016/0040-4020(96)00166-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of two tripodal iron chelating agents based on 8-hydroxyquinoline is described. The ligands consist of tris(2-aminoethylamine) (spacer) linked in 2- or 7- position to three 8-hydroxyquinoline units (allowing the complexation of iron). NMR study of these ligands in DMSO-d(6) solutions evidence intramolecular H-bond networks inducing conformational changes in relation to the protonation state of the tertiary amine.

引用

页码：4659 / 4672

页数：14

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