Progress of succinic acid production from renewable resources: Metabolic and fermentative strategies

被引：112
作者：
Jiang, Min [1 ,2 ]
Ma, Jiangfeng [1 ,2 ]
Wu, Mingke [1 ]
Liu, Rongming [1 ,3 ]
Liang, Liya [1 ,3 ]
Xin, Fengxue [1 ]
Zhang, Wenming [2 ]
Jia, Honghua [1 ,2 ]
Dong, Weiliang [1 ]
机构：
[1] Nanjing Tech Univ, State Key Lab Mat Oriented Chem Engn, Coll Biotechnol & Pharmaceut Engn, Nanjing 211800, Jiangsu, Peoples R China
[2] Nanjing Tech Univ, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Nanjing 211800, Jiangsu, Peoples R China
[3] Univ Colorado Boulder, RASEI, 4001 Discovery Dr Suite N321, Boulder, CO 80309 USA
来源：
BIORESOURCE TECHNOLOGY | 2017年 / 245卷
关键词：
Succinic acid; Renewable resources; Metabolic engineering; NADH/NAD(+); Carbon dioxide; ESCHERICHIA-COLI; ACTINOBACILLUS-SUCCINOGENES; PYRUVATE-CARBOXYLASE; MANNHEIMIA-SUCCINICIPRODUCENS; SACCHAROMYCES-CEREVISIAE; ANAEROBIOSPIRILLUM-SUCCINICIPRODUCENS; PHOSPHOENOLPYRUVATE CARBOXYLASE; BIOTECHNOLOGICAL PRODUCTION; CORYNEBACTERIUM-GLUTAMICUM; EFFICIENT PRODUCTION;
D O I：
10.1016/j.biortech.2017.05.209
中图分类号：
S2 [农业工程];
学科分类号：
0828 ;
摘要：
Succinic acid is a four-carbon dicarboxylic acid, which has attracted much interest due to its abroad usage as a precursor of many industrially important chemicals in the food, chemicals, and pharmaceutical industries. Facing the shortage of crude oil supply and demand of sustainable development, biological production of succinic acid from renewable resources has become a topic of worldwide interest. In recent decades, robust producing strain selection, metabolic engineering of model strains, and process optimization for succinic acid production have been developed. This review provides an overview of succinic acid producers and cultivation technology, highlight some of the successful metabolic engineering approaches. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1710 / 1717
页数：8
相关论文
共 83 条
  • [41] Regulation of NAD(H) pool and NADH/NAD+ ratio by overexpression of nicotinic acid phosphoribosyltransferase for succinic acid production in Escherichia coli NZN111
    Liang, Liya
    Liu, Rongming
    Wang, Guangming
    Gou, Dongmei
    Ma, Jiangfeng
    Chen, Kequan
    Jiang, Min
    Wei, Ping
    Ouyang, Pingkai
    [J]. ENZYME AND MICROBIAL TECHNOLOGY, 2012, 51 (05) : 286 - 293
  • [42] Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions
    Lin, H
    Bennett, GN
    San, KY
    [J]. BIOTECHNOLOGY AND BIOENGINEERING, 2005, 90 (06) : 775 - 779
  • [43] Effect of Sorghum vulgare phosphoenolpyruvate carboxylase and Lactococcus lactis pyruvate carboxylase coexpression on succinate production in mutant strains of Escherichia coli
    Lin, H
    San, KY
    Bennett, GN
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2005, 67 (04) : 515 - 523
  • [44] CO2 fixation for succinic acid production by engineered Escherichia coli co-expressing pyruvate carboxylase and nicotinic acid phosphoribosyltransferase
    Liu, Rongming
    Liang, Liya
    Wu, Mingke
    Chen, Kequan
    Jiang, Min
    Ma, Jiangfeng
    Wei, Ping
    Ouyang, Pingkai
    [J]. BIOCHEMICAL ENGINEERING JOURNAL, 2013, 79 : 77 - 83
  • [45] Efficient succinic acid production from lignocellulosic biomass by simultaneous utilization of glucose and xylose in engineered Escherichia colie
    Liu, Rongming
    Liang, Liya
    Li, Feng
    Wu, Mingke
    Chen, Kequan
    Ma, Jiangfeng
    Jiang, Min
    Wei, Ping
    Ouyang, Pingkai
    [J]. BIORESOURCE TECHNOLOGY, 2013, 149 : 84 - 91
  • [46] Fermentation of xylose to succinate by enhancement of ATP supply in metabolically engineered Escherichia coli
    Liu, Rongming
    Liang, Liya
    Chen, Kequan
    Ma, Jiangfeng
    Jiang, Min
    Wei, Ping
    Ouyang, Pingkai
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2012, 94 (04) : 959 - 968
  • [47] A two-stage process for succinate production using genetically engineered Corynebacterium acetoacidophilum
    Liu, Wei
    Zheng, Pu
    Yu, Fang
    Yang, Qian
    [J]. PROCESS BIOCHEMISTRY, 2015, 50 (11) : 1692 - 1700
  • [48] Economical succinic acid production from cane molasses by Actinobacillus succinogenes
    Liu, Yu-Peng
    Zheng, Pu
    Sun, Zhi-Hao
    Ni, Ye
    Dong, Jin-Jun
    Zhu, Lei-Lei
    [J]. BIORESOURCE TECHNOLOGY, 2008, 99 (06) : 1736 - 1742
  • [49] Combinatorial modulation of galP and glk gene expression for improved alternative glucose utilization
    Lu, Jiao
    Tang, Jinlei
    Liu, Yi
    Zhu, Xinna
    Zhang, Tongcun
    Zhang, Xueli
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2012, 93 (06) : 2455 - 2462
  • [50] Succinic acid production from sucrose and molasses by metabolically engineered E. coli using a cell surface display system
    Ma, Jiangfeng
    Li, Feng
    Liu, Rongming
    Liang, Liya
    Ji, Yaliang
    Wei, Ce
    Jiang, Min
    Jia, Honghua
    Ouyang, Pingkai
    [J]. BIOCHEMICAL ENGINEERING JOURNAL, 2014, 91 : 240 - 249
123456789