Correlation of plasma B-type natriuretic peptide levels with metabolic risk markers

Background and objective: Natriuretic peptide type B (BNP) is a marker of myocardium injury. This peptide has been associated with metabolic risk markers, although controversy exists in this regard. The aim of the present study was to determine the correlation of plasma BNP levels with metabolic risk parameters. Materials and methods: A retrospective, observational study that included 152 patients, who were classified according to their clinical diagnosis as patients with metabolic syndrome. Plasma BNP levels and clinical metabolic parameters were assessed by using Spearman rank correlation coefficient. Results: A significant inverse association with weight (r=-.408; p<.0001) and BMI (r=-.443; p<.001) was obtained. While a positive significant association with systolic pressure (r=.324; p<.001) was observed. A significant decrease was found in BNP levels and components of metabolic syndrome. (p<.05). Conclusion: Based on the results from this study, we can conclude that BNP determination could be an adequate metabolic marker. (C) 2018 Elsevier Espana, S.L.U. All rights reserved.