Production and characterization of calcium phosphate (CaP) whisker-reinforced poly(ε-caprolactone) composites as bone regenerative

被引：17

作者：

Choi, Won-Young ^{[2
]}

Kim, Hyoun-Ee ^{[2
]}

Kim, Mi-Jin ^{[1
]}

Kim, Uoong-Chul ^{[1
]}

Kim, Ji-Hwan ^{[1
]}

Koh, Young-Hag ^{[1
]}

机构：

[1] Korea Univ, Dept Dent Lab Sci & Engn, Seoul 136703, South Korea

[2] Seoul Natl Univ, Dept Mat Sci & Engn, Seoul 151742, South Korea

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2010年 / 30卷 / 08期

关键词：

Poly(epsilon-caprolactone); Hydroxyapatite; Composites; Whiskers; HYDROXYAPATITE-POLYCAPROLACTONE COMPOSITES; SYNTHETIC OCTACALCIUM PHOSPHATE; SOLVENT-CAST; MORPHOLOGY; SPHERES;

D O I：

10.1016/j.msec.2010.07.018

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Calcium phosphate (Cap) whisker-reinforced poly(epsilon-caprolactone) (PCL) composites with various CaP contents (0, 5, 10, and 20 wt.%) were prepared by dispersing CaP whiskers in a PCL solution. To accomplish this. CaP whiskers were synthesized by treating tricalcium phosphate (TCP) powders in a hydrogen peroxide (H2O2) solution at 90 degrees C for 48 h. All the prepared composites showed well dispersed CaP whiskers in the PCL matrix without severe agglomeration. As the CaP content was increased from 0 to 20 wt.%, the ultimate tensile strength decreased from 13.2 +/- 0.9 to 8.8 +/- 0.4 MPa, while the elastic modulus increased significantly from 173 +/- 21 to 334 +/- 24 MPa. In addition, the addition of CaP whiskers to the PCL matrix improved the biocompatibility of the composites remarkably. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：1280 / 1284

页数：5

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