Skin neoplasm diagnostics using combined spectral method in visible and near infrared regions

被引：0

作者：

Zakharov, V. P. ^{[1
]}

Bratchenko, I. A. ^{[1
]}

Artemyev, D. N. ^{[1
]}

Myakinin, O. O. ^{[1
]}

Khristoforova, Yu. A. ^{[1
]}

Vrakova, M. G. ^{[1
]}

机构：

[1] Samara State Aerosp Univ, Laser & Biotech Syst Dept, Samara, Russia

来源：

2015 INTERNATIONAL CONFERENCE ON BIOPHOTONICS (BIOPHOTONICS) | 2015年

关键词：

optical diagnostics; Raman spectroscopy; autofluorescence; skin neoplasms; RAMAN-SPECTROSCOPY; AUTOFLUORESCENCE;

D O I：

暂无

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Extensive study of skin tumors diagnosis was performed involving combined Raman spectroscopy and autofluorescence analysis in visible and near infrared regions. Proposed Raman spectroscopy phase method allows to reach 88.5% of accuracy for ex vivo skin cancer (malignant melanoma) diagnosis. Autofluorescence analysis in NIR region increases the specificity by 11%. Adding of autofluorescence analysis in visible region allows to increase final accuracy by 3-5%. Registration of autofluorescence in NIR region is realized in one unit with Raman spectroscopy. Thus, the proposed method allows detect the tumor presence rapidly using the AF determination of its boundary and determines tumor type. The high efficiency and speed of the performing study indicate the potential capabilities of the method for malignant melanoma detection with high accuracy, more than 95%.

引用

页码：108 / 111

页数：4

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