Tandem metal- and organocatalysis in sequential hydroformylation and enantioselective aldol reactions

被引：73

作者：

Chercheja, Serghei ^{[1
]}

Eilbracht, Peter ^{[1
]}

机构：

[1] Univ Dortmund, Fachbereich Chem Organ Chem 1, D-44227 Dortmund, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 11-12期

关键词：

aldol reaction; hydroformylation; organocatalysis; tandem catalysis;

D O I：

10.1002/adsc.200700160

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Metal-catalysed hydroformylation is successfully combined with organocatalysed stereoselective aldol addition into a tandem reaction sequence. This novel type of "tandem catalysis" allows access to complex molecular systems with high levels of enantioselectivity, using simple starting materials and an amino acid as the chiral catalyst.

引用

页码：1897 / 1905

页数：9

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